2-Methylpropanedioic Acid CAS 516-05-2

1. 2-Methylpropanedioic acid is a vital intermediate in the metabolism of fat and protein and serves as a clinical biomarker for functional vitamin B12 status .
2. 2-Methylpropanedioic acid CAS 516-05-2 can be used as a substrate in esterification reactions by various catalysts and in the synthesis of malonic acid half thioester (MAHT) .
3. 2-Methylpropanedioic acid is studied for its role in metabolic disorders such as methylmalonic aciduria and its neurotoxic effects on mitochondrial function .

1. Store 2-Methylpropanedioic acid powder at -20°C for up to 3 years or at 4°C for up to 2 years; in solvent, store at -80°C for 6 months or -20°C for 1 month .
2. Keep 2-Methylpropanedioic acid CAS 516-05-2 away from strong oxidizing/reducing agents, strong acids, and strong alkalis, as it is incompatible with these materials .
3. Handle 2-Methylpropanedioic acid using appropriate personal protective equipment including safety goggles and protective gloves; avoid dust formation and inhalation .

1. Isolate the spill area, use full personal protective equipment, and avoid breathing dust or vapors .
2. Absorb solutions of 2-Methylpropanedioic acid CAS 516-05-2 with finely-powdered liquid-binding material (diatomite, universal binders), collect into sealed, labeled containers, and decontaminate surfaces by scrubbing with alcohol .
3. Prevent spilled 2-Methylpropanedioic acid from entering drains or waterways; dispose of contaminated material according to local environmental regulations .

1. 2-Methylpropanedioic acid is classified with GHS signal word "Warning" and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) .
2. 2-Methylpropanedioic acid CAS 516-05-2 is considered non-hazardous for transport (DOT, IMDG, IATA) and is stable under recommended storage conditions .
3. During combustion, 2-Methylpropanedioic acid may emit irritant fumes; use water spray, dry chemical, foam, and carbon dioxide fire extinguisher for firefighting .