3-Chloro-2-fluoroaniline CAS 2106-04-9

1. Acts as a key intermediate for synthesizing anti-cancer drugs like gefitinib and erlotinib targeting epidermal growth factor receptors.
2. Serves 3-Chloro-2-fluoroaniline CAS 2106-04-9 as a core building block for manufacturing selective agrochemicals with enhanced fungicidal and insecticidal properties.
3. Functions 3-Chloro-2-fluoroaniline as a reactive reagent for diazotization and coupling reactions in fine organic synthesis and heterocyclic compound preparation.
4. Serves as a precursor for producing specialty fluorinated materials including organic dyes and electronic intermediates.

1. Store in sealed amber glass containers at 10–25℃ in a cool, dry and well-ventilated area away from direct sunlight.
2. Keep 3-Chloro-2-fluoroaniline separated from strong oxidants, acids and halogens to avoid decomposition and toxic fume emission.
3. Wear nitrile gloves, chemical safety goggles and a vapor respirator during handling, weighing and transfer operations.
4. Avoid 3-Chloro-2-fluoroaniline contact with skin and eyes; dispose of waste residues via licensed hazardous chemical disposal services.

1. Chloro-fluoro substitution enhances the molecular stability and target specificity of final pharmaceutical and agrochemical products.
2. Reactive 3-Chloro-2-fluoroaniline amino group enables efficient molecular modification and derivatization for diverse synthetic pathways.
3. Exhibits good solubility in organic solvents such as ethanol and toluene, fitting various reaction systems.
4. Delivers 3-Chloro-2-fluoroaniline high chemical purity and consistent reactivity, suitable for both lab-scale R&D and industrial-scale production.

This chemical is classified as acute oral toxicity (Category 4, H302) and irritant (Xi) with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). 3-Chloro-2-fluoroaniline is incompatible with strong oxidizers, acids and anhydrides; improper mixing may trigger exothermic reactions or release toxic chlorine-containing fumes. Prolonged skin contact can cause redness and chemical burns, while inhalation of vapors may induce respiratory discomfort. 3-Chloro-2-fluoroaniline is classified as a hazardous chemical with UN number 2811 (Packing Group III).