3′-Hydroxyacetophenone CAS 121-71-1

1. 3′-Hydroxyacetophenone is a key intermediate in pharmaceutical synthesis, notably for preparing the Alzheimer's drug Rivastigmine, as well as anti-inflammatory and analgesic medications . It is also used to synthesize chalcones and flavonoids investigated as anti-tuberculosis agents .
2. 3′-Hydroxyacetophenone CAS 121-71-1 serves as a versatile building block in organic synthesis for Friedel-Crafts acylation reactions and the production of fine chemicals, dyes, and fragrances .
3. Applications of 3′-Hydroxyacetophenone also include its use in botanical studies as a phytoanticipin with antifungal activity against *Fusarium oxysporum*, and as a reagent in analytical chemistry .

1. Store 3′-Hydroxyacetophenone in a tightly sealed container in a cool, dry, and well-ventilated place. Recommended storage temperatures vary from refrigeration (0-8 °C) to -20°C for long-term stability, and the container should be protected from light .
2. Keep 3′-Hydroxyacetophenone away from strong oxidizing agents and strong bases to prevent hazardous reactions or decomposition .
3. Always 3′-Hydroxyacetophenone CAS 121-71-1 use appropriate personal protective equipment (PPE) including chemical-resistant gloves (e.g., nitrile), safety goggles, and protective clothing; avoid breathing dust and ensure adequate ventilation when handling 3′-Hydroxyacetophenone .

1. For a spill of 3′-Hydroxyacetophenone, avoid dust formation; carefully sweep up or collect the solid using a clean, non-sparking tool and place it into a suitable, sealed, labeled container for disposal .
2. Prevent 3′-Hydroxyacetophenone CAS 121-71-1 from entering drains or waterways, as discharge into the environment should be avoided .
3. Personnel must wear suitable PPE during cleanup; dispose of 3′-Hydroxyacetophenone and all contaminated materials in accordance with local, state, and federal environmental regulations .

1. 3′-Hydroxyacetophenone is classified as causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It may be harmful if swallowed (H302) .
2. 3′-Hydroxyacetophenone has a flash point of 296°C and is combustible; thermal decomposition or combustion can produce toxic and irritating fumes, including carbon oxides .
3. Always 3′-Hydroxyacetophenone CAS 121-71-1 consult the specific Safety Data Sheet (SDS) for 3′-Hydroxyacetophenone for complete hazard information, first-aid procedures (P305+P351+P338 for eyes, P302+P352 for skin), and handling instructions; precautionary statements include P280 (wear protective gloves/eye protection) .