4-(Chloromethyl)benzoyl Chloride CAS 876-08-4

1. 4-(Chloromethyl)benzoyl chloride is primarily used as a key bifunctional reagent in organic synthesis for introducing both benzoyl and chloromethyl groups.
2. 4-(Chloromethyl)benzoyl chloride CAS 876-08-4 serves as an intermediate in the production of pharmaceuticals, agrochemicals, and liquid crystals.
3. 4-(Chloromethyl)benzoyl chloride is employed in polymer chemistry for modifying resins and in peptide synthesis as a coupling agent.

1. Store 4-(Chloromethyl)benzoyl chloride in a tightly sealed, moisture-proof container under an inert atmosphere (e.g., nitrogen) in a cool, dry, well-ventilated, and dedicated area.
2. Keep 4-(Chloromethyl)benzoyl chloride CAS 876-08-4 strictly separated from water, alcohols, amines, strong bases, and oxidizing agents to prevent violent reactions.
3. Handle 4-(Chloromethyl)benzoyl chloride with extreme care using sealed systems or dedicated equipment; avoid any exposure to air or humidity due to its rapid hydrolysis.

1. Immediately evacuate the area, isolate the spill, and ensure forced ventilation. Only trained specialists in full chemical protective gear and independent breathing apparatus should approach.
2. Do not use water. Cover 4-(Chloromethyl)benzoyl chloride CAS 876-08-4 the spill with dry sand or other inert, non-combustible absorbent. Collect into a sealed, labeled container for highly hazardous corrosive waste.
3. Neutralize residues carefully with alkaline solids (e.g., sodium carbonate), then collect as hazardous waste. Prevent any contact with water or entry into drains. Professional hazardous waste disposal is required.

1. 4-(Chloromethyl)benzoyl chloride is highly toxic, corrosive, and causes severe skin burns, eye damage, and respiratory damage. It is fatal if inhaled, swallowed, or in contact with skin.
2. 4-(Chloromethyl)benzoyl chloride CAS 876-08-4 reacts violently with water, releasing toxic and corrosive gases (hydrogen chloride, phosgene). It is a lachrymator and toxic to aquatic life.
3. Full protective equipment (acid-resistant gloves, face shield, chemical-resistant clothing, self-contained breathing apparatus) is mandatory. Handle only in a sealed glove box or fume hood with strict protocols. Consult the Safety Data Sheet before any use.