4-Fluorophenol CAS 371-41-5

1. 4-Fluorophenol is a key intermediate in synthesizing pharmaceuticals including the gastrointestinal drug cisapride and the antimalarial agent amodiaquine .
2. The compound serves as a building block in agrochemicals to enhance crop resistance, such as 4-fluorophenoxyacetic acid for pest suppression in cereals .
3. 4-Fluorophenol CAS 371-41-5 is also utilized in material science as a monomer for engineering plastics like poly(arylene ether sulfone)s with high thermal resistance .

1. Store 4-Fluorophenol in a tightly sealed container under inert gas (argon filling) at refrigerated temperatures between 2-8°C, protected from light and air .
2. Keep 4-Fluorophenol CAS 371-41-5 strictly away from strong oxidizing agents and strong bases due to incompatibility and to prevent hazardous decomposition .
3. Handle 4-Fluorophenol using appropriate personal protective equipment including nitrile gloves, safety goggles with side-shields, and in a fume hood to avoid dust and vapor inhalation .

1. Isolate the spill area, eliminate ignition sources, and avoid dust generation; sweep up solid 4-Fluorophenol into sealed, labeled containers using non-sparking tools .
2. Prevent spilled 4-Fluorophenol CAS 371-41-5 from entering drains or waterways, as discharge into the environment must be avoided .
3. Personnel cleaning 4-Fluorophenol spills must wear full protective equipment including self-contained breathing apparatus and dispose of waste according to hazardous material regulations (UN 2928, Class 6.1, PG II) .

1. 4-Fluorophenol is harmful if swallowed (H302), in contact with skin (H312), or if inhaled (H332) .
2. 4-Fluorophenol CAS 371-41-5 causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) with GHS signal word "Warning" .
3. Combustion of 4-Fluorophenol produces toxic fumes including carbon oxides and hydrogen fluoride, and intraperitoneal LD50 in mouse is 312 mg/kg .