Acetyl Chloride CAS 75-36-5

1. Acetyl chloride acts as a reagent for the preparation of esters and amides of acetic acid .
2. Acetyl chloride CAS 75-36-5 is a key reactant in Friedel-Crafts reactions for the introduction of an acetyl group into aromatic compounds .
3. Acetyl chloride serves as a starting material in the production of pharmaceuticals and as a synthetic organic intermediate .

1. Store Acetyl chloride in a tightly sealed container in a cool, dry, well-ventilated place, as Acetyl chloride is moisture sensitive and reacts violently with water .
2. Keep Acetyl chloride CAS 75-36-5 away from heat, sparks, and open flames; Acetyl chloride is a highly flammable liquid (H225) with a flash point of 4-5°C .
3. Handle Acetyl chloride using appropriate personal protective equipment, as Acetyl chloride is corrosive and causes severe skin burns and eye damage (H314) .

1. Isolate the spill area, eliminate all ignition sources, and wear full protective equipment including self-contained breathing apparatus before handling Acetyl chloride .
2. Contain Acetyl chloride CAS 75-36-5 using dry, non-combustible absorbent material like sand; DO NOT use water and prevent entry into drains .
3. Personnel cleaning Acetyl chloride spills must avoid environmental release, as Acetyl chloride is harmful to aquatic life (H412) .

1. Acetyl chloride is classified with GHS signal word "Danger" (H225, H314), is highly flammable, and reacts violently with water, producing toxic and corrosive hydrogen chloride gas .
2. Acetyl chloride CAS 75-36-5 is suspected of causing cancer (H351) and causes severe respiratory irritation (H335); in case of spill in water, large amounts of HCl gas may be produced, requiring protective action distances of up to 1.2 miles downwind .
3. Acetyl chloride has a boiling point of 52°C, vapor density of 2.7 (heavier than air), and is classified for transport as a flammable and corrosive liquid (UN 1717, Hazard Class 3/8) .