Ethyl 4-bromobutyrate CAS 2969-81-5

1. Ethyl 4-bromobutyrate is a versatile building block and alkylating agent in organic synthesis, primarily used to introduce the 4-butyrate ester group into target molecules via nucleophilic substitution .
2. Ethyl 4-bromobutyrate CAS 2969-81-5 is essential in medicinal chemistry for synthesizing pharmaceutical intermediates, including firefly luciferase inhibitors, thieno(2,3-b)-azepin-4-ones with anti-tumor potential, and zilpaterol haptens for ELISA development .
3. Applications of Ethyl 4-bromobutyrate also include its use as an intermediate for pesticides, agrochemicals, and in polymer chemistry for the synthesis of poly(2,6-dimethyl-1,4-phenylene oxide) derivatives .

1. Store Ethyl 4-bromobutyrate in a tightly sealed container in a cool, dry, well-ventilated area away from heat, sparks, and open flames; long-term storage under inert gas or refrigeration (2-8°C) is recommended to maintain stability .
2. Keep Ethyl 4-bromobutyrate strictly away from strong oxidizing agents, bases, and reducing agents to prevent hazardous reactions or decomposition .
3. Always Ethyl 4-bromobutyrate CAS 2969-81-5 use appropriate personal protective equipment (PPE) including chemical-resistant gloves (rubber/neoprene), chemical safety goggles, and protective clothing; ensure adequate ventilation or use local exhaust when handling Ethyl 4-bromobutyrate .

1. Immediately isolate the spill area and eliminate all ignition sources; contain Ethyl 4-bromobutyrate using dry sand, earth, or other inert, non-combustible absorbent material and prevent entry into drains or waterways .
2. Carefully collect Ethyl 4-bromobutyrate CAS 2969-81-5 and contaminated residue into a sealed, labeled chemical waste container for disposal; do not flush with water .
3. Personnel must wear suitable PPE including self-contained breathing apparatus if vapors are present; ensure thorough ventilation and dispose of waste in accordance with local environmental regulations .

1. Ethyl 4-bromobutyrate is a combustible liquid (flash point 58-90°C) and causes skin irritation (H315), serious eye irritation (H319), and respiratory tract irritation (H335); vapors may form explosive mixtures with air .
2. Ethyl 4-bromobutyrate is harmful if swallowed, inhaled, or absorbed through the skin; thermal decomposition or combustion produces toxic and corrosive fumes including carbon monoxide, carbon dioxide, and hydrogen bromide .
3. Always Ethyl 4-bromobutyrate CAS 2969-81-5 consult the specific Safety Data Sheet (SDS) for Ethyl 4-bromobutyrate for complete hazard information, first-aid procedures, and regulatory compliance; UN classification varies (2929 or non-hazardous for transport depending on jurisdiction) .