Tert-Butyl 2-bromo-2-methylpropanoate CAS 23877-12-5

1. tert-Butyl 2-bromo-2-methylpropanoate CAS 23877-12-5 is primarily used as an alkylating agent and intermediate in organic synthesis, particularly for pharmaceuticals and fine chemicals.
2. Tert-Butyl 2-bromo-2-methylpropanoate serves as a versatile building block for introducing the tert-butoxycarbonyl (Boc) and α-bromoisobutyryl groups, useful in polymerization initiators and peptide synthesis.
3. This compound is also utilized in polymer chemistry as an atom transfer radical polymerization (ATRP) initiator.

1. Store tert-butyl 2-bromo-2-methylpropanoate CAS 23877-12-5 in a cool, dry, well-ventilated place, protected from light and away from heat and ignition sources. Refrigeration is often recommended.
2. Keep Tert-Butyl 2-bromo-2-methylpropanoate the container tightly closed and separated from strong oxidizing agents, strong bases, and reducing agents.
3. Handle with extreme caution using appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles, face shield, and a lab coat. Always use a fume hood.

1. Immediately isolate the area, ensure ventilation, and wear full protective equipment (gloves, goggles, protective clothing, respirator).
2. Absorb Tert-Butyl 2-bromo-2-methylpropanoate spill with an inert, non-combustible material (e.g., sand, vermiculite). Place the contaminated material in a sealed, labeled hazardous waste container. **Do not use water** for cleanup.
3. Prevent the compound from entering drains, sewers, or the environment. Decontaminate surfaces with a suitable solvent, collecting all residues. Seek expert assistance if needed.

1. tert-Butyl 2-bromo-2-methylpropanoate CAS 23877-12-5 is highly toxic, corrosive, and a potent lachrymator. It causes severe skin burns, eye damage, and respiratory damage. It is harmful if swallowed or inhaled.
2. Tert-Butyl 2-bromo-2-methylpropanoate is flammable and may emit highly toxic fumes (hydrogen bromide, carbon oxides) when heated to decomposition. It reacts violently with nucleophiles.
3. Always consult the official tert-butyl 2-bromo-2-methylpropanoate Safety Data Sheet (SDS) for the most current and comprehensive hazard, handling, and regulatory information. Handle as a severe health and reactivity hazard.