Products Description
Product Name: Fmoc-His(Trt)-OH
CAS: 109425-51-6
EINECS: 439-640-4
Melting point: 150-155 °C
Boiling point: 811.7±65.0 °C
Density: 1.24±0.1 g/cm3
Specification
| Items | Specifications |
| Appearance | White crystalline powder |
| Purity | ≥99% |
| Water | ≤0.1% |
Application
1. Fmoc-His(Trt)-OH CAS 109425-51-6 is primarily used as a protected amino acid building block in solid-phase peptide synthesis (SPPS) for introducing histidine residues into peptides and proteins.
2. Fmoc-His(Trt)-OH features dual protection with an Fmoc group on the alpha-amino group and a Trityl (Trt) group on the imidazole side chain, which prevents side reactions and racemization during peptide chain elongation.
3. Fmoc-His(Trt)-OH is employed in pharmaceutical research for developing enzyme inhibitors, peptide-based therapeutics, and bioactive molecules requiring protected histidine.
4. Researchers utilize this product in Fmoc SPPS strategies, where the Trt group is cleaved simultaneously with TFA during final deprotection.
Storage and Precautions
1. Fmoc-His(Trt)-OH CAS 109425-51-6 must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture.
2. Fmoc-His(Trt)-OH should be kept at -20°C for long-term storage (up to 3 years) or at 2-8°C for shorter periods (up to 2 years) to maintain stability, and stored under inert gas due to moisture sensitivity.
3. Personnel must wear chemical-resistant gloves (nitrile rubber, minimum 0.11 mm thickness), safety goggles, and protective clothing when handling Fmoc-His(Trt)-OH, ensuring adequate ventilation in work areas.
4. Avoid inhalation of dust particles, prevent contact with skin, eyes, and clothing, and wash thoroughly after handling this substance.
Emergency response to leakage
1. Isolate the spill area, ensure adequate ventilation, and avoid dust formation when Fmoc-His(Trt)-OH CAS 109425-51-6 is released, using personal protective equipment.
2. Collect Fmoc-His(Trt)-OH by sweeping or shoveling without creating dust and place into suitable closed containers for disposal.
3. Avoid creating dust clouds when cleaning up Fmoc-His(Trt)-OH powder to prevent respiratory exposure and airborne contamination.
4. Prevent the product from entering drains or water courses, and dispose of collected material according to local environmental regulations.
Fire prevention measures
1. Fmoc-His(Trt)-OH CAS 109425-51-6 is not classified as highly flammable (NFPA fire rating of 1) but may decompose under high heat conditions, with a melting point of approximately 145°C (decomposes on heating).
2. Use dry chemical powder, carbon dioxide, alcohol-resistant foam, or water spray to extinguish fires involving the product.
3. Firefighters Fmoc-His(Trt)-OH should wear self-contained breathing apparatus and full protective gear when handling burning Fmoc-His(Trt)-OH due to hazardous decomposition gases.
4. Hazardous decomposition products formed under fire conditions include carbon oxides, nitrogen oxides (NOx), and toxic fumes.
Recommended Products
| Items | Product Name |
| 1 | N-(tert-Butoxycarbonyl)-L-alanine / Boc-Ala-OH CAS 15761-38-3 |
| 2 | Boc-Arg(Pbf)-OH CAS 200124-22-7 |
| 3 | Boc-Asn(Trt)-OH CAS 132388-68-2 |
| 4 | BOC-L-Valine CAS 13734-41-3 |
| 5 | Boc-His(Trt)-OH CAS 32926-43-5 |
| 6 | BOC-L-Isoleucine CAS 13139-16-7 |
| 7 | Boc-Lys(Boc)-OH CAS 2483-46-7 |
| 8 | BOC-D-Alanine CAS 7764-95-6 |
| 9 | Boc-Cys(Acm)-OH CAS 19746-37-3 |
| 10 | If you want to need more information,welcome to contact us at any time.
WhatsApp: +86 18317156592
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Packaging
Transportation & Payment
About Transportation
Depending on the requirements of our clients, we can give a variety of transportation options.
For smaller orders, we offer air shipping or international courier services like FedEx, DHL, TNT, EMS, and numerous other unique lines of international transit.
We can transport by sea to a specified port for bigger amounts.
Additionally, we can offer unique services based on the requirements of our clients and the characteristics of their goods.
* We can offer a range of payment options to our clients.
* When the sum is modest, clients typically pay with PayPal, Western Union, Alibaba, and other similar services.
* When the sum is significant, clients typically pay with T/T, L/C at sight, Alibaba, and so on.
* Furthermore, an increasing number of consumers will use Alipay or WeChat Pay to make payments.
FAQ
1
May I get any sample from you?
Re: Yes, of course, we'd like to provide sample to you according to your demands.
2
What is your MOQ?
Re: Usually our MOQ is 1 kg, but sometimes it is also flexible and depends on different products.
3
How long I can get my goods after payment?
Re: If shipped by couriers or air, it usually cost 5-10 days.
If shipped by sea, it usually cost 3-40 days, which depends on your destination.
4
Do you have any after-sales service?
Re: Yes, we will inform you progress of the order, such as product preparation, declaration, transportation follow-up, customs clearance assistance, technical guidance, etc.
Contact Us
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