2-Bromoaniline/o-Bromoaniline CAS 615-36-1

1. 2-Bromoaniline is a key building block in the synthesis of azo dyes for textiles and food coloring, as well as in the production of quinoline dyes .
2. o-Bromoaniline CAS 615-36-1 serves as a critical precursor in pharmaceutical development for creating analgesics, anti-inflammatory drugs, and various heterocyclic compounds like benzimidazoles and indoles .
3. 2-Bromoaniline is utilized in cross-coupling reactions (e.g., Buchwald-Hartwig, Suzuki-Miyaura) to form new carbon-nitrogen and carbon-carbon bonds, facilitating the creation of diverse biaryl structures for materials science and agrochemicals .

1. Store 2-Bromoaniline in a tightly sealed container under inert atmosphere, protected from light, at refrigerated temperatures between 0-8°C .
2. Keep o-Bromoaniline CAS 615-36-1 in a cool, well-ventilated area (ideally below 37°C) strictly away from strong oxidizing agents, acids, acid anhydrides, and acid chlorides .
3. Handle 2-Bromoaniline using appropriate personal protective equipment including chemical-resistant gloves (butyl-rubber), safety goggles, and in a fume hood to avoid breathing dust or vapors .

1. Isolate the o-Bromoaniline CAS 615-36-1 spill area, eliminate all ignition sources, and wear full protective equipment including self-contained breathing apparatus before handling 2-Bromoaniline .
2. Sweep up spilled 2-Bromoaniline using non-sparking tools into sealed, labeled containers for disposal without creating dust, and prevent entry into drains or waterways .
3. Personnel cleaning 2-Bromoaniline spills must dispose of waste through a licensed chemical destruction facility, as 2-Bromoaniline is a hazardous substance (UN 2811, Hazard Class 6.1, PG III) .

1. 2-Bromoaniline is toxic if swallowed (H301/H302), in contact with skin (H311), and if inhaled (H332), with GHS signal word "Danger" .
2. o-Bromoaniline CAS 615-36-1 causes skin irritation (H315), serious eye irritation (H319), and may cause damage to organs through prolonged exposure (H373); absorption into the body leads to methemoglobin formation causing cyanosis .
3. 2-Bromoaniline has a flash point >110°C, and combustion or thermal decomposition produces toxic fumes including carbon oxides, nitrogen oxides, and hydrogen bromide gas .