4-Iodoaniline CAS 540-37-4

1. 4-Iodoaniline serves as a key building block in the synthesis of 5-iodoindoles and 6-iodoquinolines, which are valuable pharmaceutical intermediates .
2. 4-Iodoaniline CAS 540-37-4 is used in materials science to prepare phenyl-functionalized graphene oxide (I-Ph-GO) and as a monomer for creating conductive polymers .
3. 4-Iodoaniline is employed as a reagent in spectrophotometric techniques for determining aromatic amines in analytical chemistry .

1. Store 4-Iodoaniline in a tightly sealed container under inert gas (argon filling) at 2-8°C, as 4-Iodoaniline is light and air sensitive .
2. Keep 4-Iodoaniline CAS 540-37-4 strictly away from strong oxidizing agents, acids, acid chlorides, acid anhydrides, and chloroformates due to incompatibility .
3. Handle 4-Iodoaniline using appropriate personal protective equipment including nitrile gloves, safety goggles with side-shields, and in a fume hood to avoid breathing dust and contact with skin and eyes .

1. Isolate the spill area, wear full protective equipment including self-contained breathing apparatus, and avoid dust generation when handling solid 4-Iodoaniline .
2. Sweep up spilled 4-Iodoaniline CAS 540-37-4 using non-sparking tools into sealed, labeled containers for disposal without creating dust .
3. Prevent spilled 4-Iodoaniline from entering drains or waterways, and dispose of waste through a licensed chemical destruction facility .

1. 4-Iodoaniline is harmful if swallowed (LD50 oral rat: 523 mg/kg), toxic in contact with skin (H311), and harmful if inhaled (H332) .
2. 4-Iodoaniline CAS 540-37-4 causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) with GHS signal word "Warning" .
3. Absorption of 4-Iodoaniline into the body leads to the formation of methemoglobin, which in sufficient concentration causes cyanosis .