4-Methoxybenzoyl Chloride CAS 100-07-2

1. 4-Methoxybenzoyl chloride CAS 100-07-2 is a key intermediate in synthesizing pharmaceuticals, particularly anti-inflammatory and analgesic drugs.
2. 4-Methoxybenzoyl chloride is used in the synthesis of stilbene and dihydrostilbene derivatives with potential anticancer activity, as well as coumarin dimers with potential HIV-1 activity .
3. 4-Methoxybenzoyl chloride serves as an acylating agent in organic synthesis, polymer chemistry, and agrochemical formulations .

1. Store 4-Methoxybenzoyl chloride CAS 100-07-2 in a tightly sealed container under inert gas at 2-8°C, protected from light, air, and moisture .
2. Keep 4-Methoxybenzoyl chloride strictly away from strong oxidizing agents, bases, alcohols, and water, as it decomposes and reacts violently with moisture .
3. Handle 4-Methoxybenzoyl chloride using appropriate personal protective equipment including face shield, gloves, and protective clothing in a fume hood .

1. Isolate the spill 4-Methoxybenzoyl chloride CAS 100-07-2 area (minimum 50 meters), eliminate ignition sources, and cover 4-Methoxybenzoyl chloride with dry inert material like sand, avoiding any water contact .
2. Collect 4-Methoxybenzoyl chloride using clean, non-sparking tools into sealed, labeled corrosion-resistant containers .
3. Personnel cleaning 4-Methoxybenzoyl chloride spills must wear full protective equipment including self-contained breathing apparatus and dispose of waste according to hazardous material regulations.

1. 4-Methoxybenzoyl chloride CAS 100-07-2 is corrosive, causing severe skin burns and serious eye damage (H314, H318), with NFPA health rating of 3 (serious hazard) .
2. 4-Methoxybenzoyl chloride is water-reactive and air-reactive, reacting exothermically with moisture to form hydrochloric acid and insoluble anisic acid .
3. 4-Methoxybenzoyl chloride has a flash point of 87°C, decomposes when heated to emit toxic hydrogen chloride fumes, and may explode spontaneously at room temperature .