P-Toluoyl Chloride CAS 874-60-2

1. p-Toluoyl chloride is widely utilized as a reagent in organic synthesis to introduce the p-toluoyl group into target molecules, facilitating the creation of pharmaceuticals and specialty chemicals .
2. The compound serves as a key intermediate in polymer chemistry for synthesizing specialty polymers with tailored properties for specific industrial applications .
3. p-Toluoyl chloride CAS 874-60-2 is employed in the synthesis of agrochemicals, including an investigational anthelmintic compound studied for its efficacy against gastrointestinal parasites .

1. Store p-Toluoyl chloride in a tightly sealed container under inert gas (argon filling) in a cool, dry place at refrigerated temperatures (2-8°C), protected from light and moisture .
2. Keep p-Toluoyl chloride CAS 874-60-2 strictly away from strong oxidizing agents, bases, alcohols, amines, and metals, as p-Toluoyl chloride is incompatible and reacts violently with water and moisture .
3. Handle p-Toluoyl chloride using appropriate personal protective equipment including tightly fitting safety goggles, face shield, chemical-resistant gloves, and in a fume hood to avoid breathing vapors .

1. Isolate the spill area, eliminate all ignition sources, and contain p-Toluoyl chloride using dry inert absorbent material (e.g., sand), preventing any contact with water .
2. Collect spilled p-Toluoyl chloride CAS 874-60-2 using an electrically protected vacuum cleaner or by wet-brushing into sealed, labeled corrosion-resistant containers for disposal according to local regulations .
3. Personnel cleaning p-Toluoyl chloride spills must wear full protective equipment including self-contained breathing apparatus and prevent entry into drains or waterways .

1. p-Toluoyl chloride is corrosive, causing severe skin burns and serious eye damage (H314, H318), with an NFPA health rating of 3 (serious hazard) .
2. p-Toluoyl chloride CAS 874-60-2 is a combustible liquid (flash point 82°C) and reacts with water, releasing corrosive hydrogen chloride gas; thermal decomposition produces toxic fumes including carbon oxides and hydrogen chloride .
3. p-Toluoyl chloride is classified for transport as a corrosive liquid (UN 3265, Hazard Class 8, Packing Group II) and is for research use only, not for human or veterinary use .