Ammonium Thioglycolate CAS 5421-46-5

1. Ammonium thioglycolate is primarily used in cosmetic and hair care products as a reducing agent in permanent wave lotions, hair straighteners, and depilatories at concentrations up to 15.2% (as thioglycolic acid) .
2. Ammonium thioglycolate CAS 5421-46-5 serves as a thiol-functionalizing agent in materials science, for example, to modify eggshell membranes for the biosorption of toxic heavy metal ions like Hg(II), Pb(II), and Cd(II) from wastewater .
3. Ammonium thioglycolate is used as a biochemical reagent for the reductive cleavage of disulfide bonds and as a raw material in the synthesis of other thioglycolate salts and pharmaceutical intermediates .

1. Store Ammonium thioglycolate in a tightly sealed container in a cool, dry, and well-ventilated place, protected from light and away from acids, as it decomposes when heated and is incompatible with acids .
2. Keep Ammonium thioglycolate CAS 5421-46-5 in a corrosive-resistant container in a freezer or cool, dark location (<15°C) to prevent degradation .
3. Handle Ammonium thioglycolate using appropriate personal protective equipment including chemical-resistant gloves and safety goggles, and avoid breathing vapors as it is a strong allergen and causes contact dermatitis .

1. Isolate the spill area (at least 50 meters for liquids), and wear full protective equipment including a NIOSH-approved respirator with an organic vapor/acid gas cartridge .
2. Absorb liquid Ammonium thioglycolate CAS 5421-46-5 with dry inert material like sand, collect using non-sparking tools into sealed, labeled containers, and prevent entry into drains or waterways .
3. Personnel cleaning Ammonium thioglycolate spills must dispose of waste through licensed chemical destruction, as Ammonium thioglycolate is classified for transport as a toxic and corrosive liquid (UN 2922 or UN 2810, Hazard Class 6.1/8) .

1. Ammonium thioglycolate is classified with GHS signal word "Danger" and is toxic if swallowed (H301, LD50 mouse ip: 100 mg/kg), fatal if inhaled (H330), and harmful in contact with skin (H312) .
2. Ammonium thioglycolate CAS 5421-46-5 causes severe skin burns (H314), serious eye damage (H318), and may cause an allergic skin reaction (H317), leading to irritant or allergic contact dermatitis in hairdressers and clients .
3. Ammonium thioglycolate is a colorless to pale pink liquid with a repulsive, skunk-like odor, is miscible with water, combustible, and when heated to decomposition emits very toxic fumes including nitrogen oxides, sulfur oxides, and ammonia .