Ethyl 4-nitrophenylacetate CAS 5445-26-1

1. Ethyl 4-nitrophenylacetate CAS 5445-26-1 serves as a crucial substrate in lipase-catalyzed reactions, achieving 100% conversion in aminolysis for synthesizing substituted phenylacetamides .
2. Ethyl 4-nitrophenylacetate is frequently utilized as a synthetic intermediate in organic chemistry for hydrolysis to produce p-nitrophenol and for developing derivatives with biological activity .
3. Ethyl 4-nitrophenylacetate is employed in biochemical assays to study enzyme kinetics and mechanisms, particularly for evaluating hydrolases through spectrophotometric monitoring .

1. Store Ethyl 4-nitrophenylacetate CAS 5445-26-1 in a tightly sealed container in a cool, dry place, protected from light and away from oxidizing agents .
2. Keep Ethyl 4-nitrophenylacetate containers closed when not in use and ensure storage areas have good ventilation or exhaust systems .
3. Handle Ethyl 4-nitrophenylacetate using appropriate personal protective equipment including dust masks, safety glasses, and gloves to avoid contact and inhalation .

1. Isolate Ethyl 4-nitrophenylacetate CAS 5445-26-1 the spill area and avoid dust formation; sweep up solid Ethyl 4-nitrophenylacetate into sealed, labeled containers without dispersing the material .
2. Prevent spilled Ethyl 4-nitrophenylacetate from entering drains or waterways during cleanup operations .
3. Personnel cleaning Ethyl 4-nitrophenylacetate spills must wear suitable protective equipment and dispose of waste according to local environmental regulations .

1. Ethyl 4-nitrophenylacetate CAS 5445-26-1 causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) .
2. Ethyl 4-nitrophenylacetate is combustible and thermal decomposition produces toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides .
3. Ethyl 4-nitrophenylacetate is classified with GHS signal word "Warning" and safety phrase S24/25 recommends avoiding skin and eye contact .