4-Bromofluorobenzene CAS 460-00-4

1. 4-Bromofluorobenzene is a key intermediate in pharmaceutical synthesis, particularly for developing anti-cancer and anti-inflammatory drugs, and in agrochemical development for creating effective pesticides and herbicides .
2. 4-Bromofluorobenzene CAS 460-00-4 is widely used as an analytical standard and surrogate in environmental testing, such as in GC-MS methods for determining BTEX compounds in groundwater and assessing diesel toxicity .
3. Applications of 4-Bromofluorobenzene also include its use in material science for formulating advanced polymers and resins, and in research as a building block for fluorescent probes and complex organic molecules .

1. Store 4-Bromofluorobenzene in a tightly sealed container in a cool, dry, and well-ventilated place, away from heat, sparks, and open flames . Recommended storage temperatures range from 0-8°C to 2-30°C, protected from light .
2. Keep 4-Bromofluorobenzene strictly away from strong oxidizing agents due to incompatibility . Containers must be grounded/bonded to prevent electrostatic discharge, as vapors may form explosive mixtures with air .
3. Always 4-Bromofluorobenzene CAS 460-00-4 use appropriate personal protective equipment (PPE) including chemical-resistant gloves, tightly fitting safety goggles with faceshield, and flame-retardant antistatic protective clothing; handle only with adequate ventilation or in a fume hood .

1. Immediately isolate the spill area, eliminate all ignition sources, and ensure adequate ventilation. Contain 4-Bromofluorobenzene using dry, inert, non-combustible absorbent material (e.g., sand, earth, vermiculite) and DO NOT use water jet .
2. Carefully collect 4-Bromofluorobenzene CAS 460-00-4 using non-sparking, explosion-proof tools into sealed, labeled chemical waste containers for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must wear full chemical-protective equipment including self-contained breathing apparatus (SCBA) during cleanup . 4-Bromofluorobenzene is classified for transport (UN1993, Hazard Class 3, PG III) .

1. 4-Bromofluorobenzene is classified as a flammable liquid (H226/H225) with a flash point of 53-60°C (closed cup) . It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) .
2. 4-Bromofluorobenzene is harmful if swallowed (H302, LD50 oral rat: 2,700 mg/kg), harmful if inhaled (H332, LC50 rat: 18,000 mg/m³/4h), and toxic in contact with skin (H311/H312) . Thermal decomposition or combustion produces toxic and corrosive fumes including carbon oxides, hydrogen bromide gas, and hydrogen fluoride .
3. Always consult 4-Bromofluorobenzene CAS 460-00-4 the specific Safety Data Sheet (SDS) for 4-Bromofluorobenzene for complete hazard information, first-aid procedures (P305+P351+P338 for eyes, P303+P361+P353 for skin, P301+P310 for ingestion), and handling instructions .