Indole-3-carboxaldehyde CAS 487-89-8

1. Indole-3-carboxaldehyde CAS 487-89-8 is a key intermediate and a promising scaffold in drug design, used to synthesize derivatives with diverse biological activities, including anti-inflammatory, anti-cancer, anti-bacterial, anti-fungal, and anti-HIV properties .
2. Indole-3-carboxaldehyde is widely utilized in pharmaceutical development, for example, as an intermediate in the synthesis of agents targeting neurological disorders . It also serves as a versatile building block for creating ligands in Schiff base synthesis, polymers, and chromophores.
3. Applications of Indole-3-carboxaldehyde extend to agricultural uses in formulating plant growth regulators, as well as roles in biochemical research on metabolic pathways and in material science for developing novel polymers and dyes .

1. Store Indole-3-carboxaldehyde CAS 487-89-8 in a tightly sealed container in a cool, dry, and well-ventilated place, protected from light and direct sunlight. Recommended storage conditions are typically between 2-8°C (refrigerated) .
2. Keep Indole-3-carboxaldehyde away from incompatible materials, including strong oxidizing agents, strong reducing agents, strong acids, and strong alkalis, to prevent decomposition .
3. Always Indole-3-carboxaldehyde use appropriate personal protective equipment (PPE), including protective gloves and safety goggles, when handling Indole-3-carboxaldehyde to avoid dust generation and contact with skin, eyes, or clothing .

1. Immediately contain the Indole-3-carboxaldehyde CAS 487-89-8 spill using inert, non-combustible absorbent material (e.g., diatomite). Avoid generating dust and ensure adequate ventilation .
2. Carefully collect Indole-3-carboxaldehyde or absorbed solutions into a sealed, labeled chemical waste container. Decontaminate surfaces and equipment by scrubbing with alcohol .
3. Prevent Indole-3-carboxaldehyde from entering drains or waterways. Personnel must wear suitable PPE during cleanup and dispose of all waste according to local, state, and federal environmental regulations .

1. Indole-3-carboxaldehyde CAS 487-89-8 is not classified as a hazardous substance or mixture according to GHS by some suppliers , but others assign a "Warning" signal word with precautionary statements . It is for research use only and not for human or veterinary use .
2. Under fire conditions, Indole-3-carboxaldehyde may decompose and emit irritant or toxic fumes . It is considered non-hazardous for transport (DOT, IATA, IMDG) . Melting point ranges are reported as 193-202°C and 194-200°C .
3. Always Indole-3-carboxaldehyde consult the specific Safety Data Sheet (SDS) for Indole-3-carboxaldehyde for complete hazard information, first-aid procedures, and handling instructions .