PIPES Disodium Salt / PIPES-2Na CAS 76836-02-7

1. Acts PIPES disodium salt CAS 76836-02-7 as a zwitterionic Good's buffer in low-temperature cell culture to maintain stable pH for sensitive cell lines and microbial cultures.
2. Serves PIPES-2Na as a pH stabilizer in protein crystallization and enzyme activity assays to preserve biomolecular conformation and function.
3. Functions as a buffer in flow cytometry and immunofluorescence experiments to ensure reliable results for cell surface marker analysis.

1. Store PIPES disodium salt in sealed moisture-proof containers at 15-25℃ in a cool, dry, dark area away from direct sunlight and oxidizing agents.
2. Keep PIPES-2Na separated from strong acids and heavy metal salts to prevent precipitation and loss of buffering capacity.
3. Wear nitrile gloves, safety goggles, and a dust mask during handling to avoid skin contact and accidental dust inhalation.

1. Higher PIPES disodium salt water solubility than PIPES free acid simplifies the preparation of high-concentration buffer solutions for large-scale experiments.
2. Negligible PIPES-2Na metal ion chelation makes it ideal for experiments involving metal-dependent enzymes and ion channel studies.
3. Stable buffering performance in the weakly acidic to neutral range ensures reproducible outcomes in sensitive biological assays.

- GHS Classification: Irritant (GHS07, Xi), causes skin irritation (H315), causes serious eye irritation (H319), may cause respiratory irritation (H335).
- Prolonged PIPES disodium salt skin contact can lead to redness, itching, and dryness; eye contact may result in tearing and temporary discomfort.
- Non-flammable PIPES-2Na and chemically stable under recommended storage conditions; avoid temperatures above 320℃ to prevent thermal decomposition.
- UN Number: Not listed as a hazardous substance for general transport; classified as a non-dangerous good under normal conditions.