5-Iodouracil CAS 696-07-1

1. 5-Iodouracil CAS 696-07-1 is primarily used in anticancer research, where derivatives exhibit potent cytotoxic effects against various cancer cell lines, including HepG2, by inhibiting nucleic acid synthesis .
2. 5-Iodouracil serves as a building block in pharmaceutical development for synthesizing new drugs, and is investigated for its antiviral potential to inhibit viral replication .
3. 5-Iodouracil is employed in biochemical studies to explore DNA and RNA interaction mechanisms, enhancing understanding of genetic processes and enzyme inhibition .
4. Researchers utilize this product as a bacterial detection agent and in diagnostic applications for identifying viral infections through nucleic acid interactions .

1. 5-Iodouracil CAS 696-07-1 must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light due to light sensitivity, at 2-8°C for short-term or -20°C for long-term storage .
2. 5-Iodouracil should be kept away from oxidizing agents and incompatible materials such as strong acids/alkalis and strong oxidizing/reducing agents to maintain stability .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and impervious protective clothing when handling 5-Iodouracil, as it causes skin and serious eye irritation .
4. Avoid inhalation of dust particles, ensure adequate ventilation in work areas (preferably a chemical fume hood), and wash thoroughly after handling this substance .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including suitable respirator when 5-Iodouracil CAS 696-07-1 is released .
2. Collect 5-Iodouracil by vacuuming or sweeping without creating dust, or absorb with finely-powdered liquid-binding material (diatomite, universal binders), and place into suitable closed containers for disposal .
3. Avoid creating dust clouds when cleaning up 5-Iodouracil powder to prevent respiratory exposure, and decontaminate surfaces and equipment by scrubbing with alcohol .
4. Prevent 5-Iodouracil from entering drains or water courses, and dispose of collected material according to local, state, and federal environmental regulations .

1. 5-Iodouracil CAS 696-07-1 is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including nitrogen oxides, carbon monoxide, carbon dioxide, and hydrogen iodide .
2. Use water 5-Iodouracil spray, dry chemical powder, carbon dioxide, or chemical foam to extinguish fires involving the product .
3. Firefighters should wear self-contained breathing apparatus and full protective gear when handling burning 5-Iodouracil due to hazardous decomposition gases and irritant fumes .
4. During combustion, may emit irritant fumes; contain fire runoff from dilution water to prevent environmental contamination and pollution .