N-Benzyloxycarbonyl-L-proline CAS 1148-11-4

1. N-Benzyloxycarbonyl-L-proline is primarily used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis for introducing proline residues into peptides .
2. N-Benzyloxycarbonyl-L-proline CAS 1148-11-4 serves as a potent in vitro and in vivo inhibitor of prolidase, a specific peptidase that cleaves dipeptides with C-terminal prolyl and hydroxyprolyl residues .
3. N-Benzyloxycarbonyl-L-proline is employed in the synthesis of N-(L-Prolyl)-β-alanine and other biologically active peptides, including hormones such as oxytocin and vasopressin .
4. Researchers utilize this product to study prolidase deficiency disorders and to investigate enzyme mechanisms in proline metabolism .

1. N-Benzyloxycarbonyl-L-proline must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment at 2-8°C, with long-term storage recommended at -20°C for up to 3 years .
2. N-Benzyloxycarbonyl-L-proline CAS 1148-11-4 should be protected from light, moisture, and incompatible materials such as strong oxidizing agents to maintain stability .
3. Personnel must wear chemical-resistant gloves, safety goggles, and protective clothing when handling N-Benzyloxycarbonyl-L-proline, as it may cause irritation to eyes, respiratory system, and skin .
4. Avoid inhalation of dust particles, work in a well-ventilated area, and follow safety statements S22 (Do not breathe dust) and S24/25 (Avoid contact with skin and eyes) .

1. Isolate the spill area, ensure adequate ventilation, and avoid dust formation when N-Benzyloxycarbonyl-L-proline is released, using personal protective equipment .
2. Collect N-Benzyloxycarbonyl-L-proline CAS 1148-11-4 by sweeping or shoveling without creating dust and place into suitable closed containers for disposal .
3. Avoid creating dust clouds when cleaning up N-Benzyloxycarbonyl-L-proline powder to prevent respiratory exposure and airborne contamination .
4. Prevent the product from entering drains or water courses, and dispose of collected material according to local environmental regulations .

1. N-Benzyloxycarbonyl-L-proline is not classified as highly flammable but may decompose under high heat conditions, with a flash point of approximately 215°C .
2. Use dry chemical powder, carbon dioxide, alcohol-resistant foam, or water spray to extinguish fires involving the product .
3. Firefighters N-Benzyloxycarbonyl-L-proline CAS 1148-11-4 should wear self-contained breathing apparatus and full protective gear when handling burning N-Benzyloxycarbonyl-L-proline due to hazardous decomposition gases .
4. Hazardous decomposition products formed under fire conditions include carbon oxides and nitrogen oxides (NOx) .