Dibenzosuberone CAS 1210-35-1

1. Dibenzosuberone CAS 1210-35-1 is a key intermediate for synthesizing active pharmaceutical ingredients (APIs), most notably the tricyclic antidepressant drug amitriptyline .
2. Dibenzosuberone is a fundamental building block for producing novel disubstituted dibenzosuberone derivatives that act as highly potent and selective inhibitors of p38α mitogen-activated protein (MAP) kinase, an important target for anti-inflammatory drugs .
3. Dibenzosuberone is also used in regioselective bromination reactions to produce intermediates essential for preparing other dibenzosuberone derivatives .

1. Store Dibenzosuberone CAS 1210-35-1 in a tightly sealed container in a cool, dry, and well-ventilated place, away from incompatible materials . Recommended storage temperatures vary from 4 °C to -20 °C, especially for long-term stability .
2. Keep Dibenzosuberone strictly away from strong oxidizing agents, strong bases, and reducing agents due to incompatibility .
3. Handle Dibenzosuberone using appropriate personal protective equipment including safety glasses, chemical-resistant gloves, and protective clothing, as it may cause skin irritation and serious eye irritation .

1. Isolate the spill area, use personal protective equipment, and avoid dust formation .
2. Sweep up spilled Dibenzosuberone or soak it up with inert absorbent material, then place into a sealed, labeled container for disposal . Prevent the product from entering drains .
3. Personnel cleaning Dibenzosuberone spills must dispose of waste through a licensed chemical destruction facility or by controlled incineration with flue gas scrubbing .

1. Dibenzosuberone CAS 1210-35-1 is classified with GHS signal word "Warning" and causes skin irritation (H315), serious eye irritation (H319), and may cause an allergic skin reaction (H317) .
2. Some sources indicate Dibenzosuberone may be harmful if swallowed . Toxicological properties have not been fully investigated; thus, avoid inhalation, skin contact, and eye contact .
3. Dibenzosuberone is stable under recommended storage conditions . In the event of a fire, thermal decomposition produces toxic and irritating fumes including carbon monoxide and carbon dioxide .