N-Formylglycine CAS 2491-15-8

1. N-Formylglycine CAS 2491-15-8 is an endogenous metabolite identified as a potential plasma biomarker for the early diagnosis of hepatocellular carcinoma (HCC) when combined with other metabolites .
2. N-Formylglycine acts as a reversible, competitive inhibitor of the enzyme succinic semialdehyde dehydrogenase, which is involved in neurotransmitter metabolism .
3. N-Formylglycine is also described as a simple dipeptide and a post-translationally generated residue with unique catalytic capabilities for biotechnology applications .

1. Store N-Formylglycine CAS 2491-15-8 powder at -20°C (stable up to 3 years) or 4°C, sealed and away from moisture. Solutions should be stored at -80°C for 6 months or -20°C for 1 month .
2. Keep N-Formylglycine in a tightly sealed container in a cool, dry, well-ventilated place. Avoid dust formation and keep away from strong oxidizing agents, acids, and bases .
3. Handle N-Formylglycine using appropriate personal protective equipment (chemical-resistant gloves, safety goggles) as it is considered a moderate to severe irritant to the skin and eyes .

1. Isolate the spill area, wear full protective equipment including a NIOSH/MSHA-approved respirator, and avoid dust generation .
2. Sweep up N-Formylglycine carefully and place it into a sealed, labeled container for disposal; do not let the product enter drains .
3. Personnel cleaning N-Formylglycine spills must dispose of waste in accordance with prevailing country, federal, state, and local environmental regulations .

1. N-Formylglycine CAS 2491-15-8 is classified with GHS signal word "Danger" by some sources and as not hazardous by others . It is toxic (contains a pharmaceutically active ingredient) and may be very toxic if swallowed (R28), irritating to skin (R38), and a risk of serious damage to eyes (R41) .
2. N-Formylglycine may be harmful if swallowed, inhaled, or absorbed through the skin. It is a moderate to severe irritant. An unreported rat LD50 is > 3 g/kg .
3. Under fire conditions, thermal decomposition of N-Formylglycine produces toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides . It is considered non-hazardous for transport .