Oxindole CAS 59-48-3

Product Name: Oxindole
CAS: 59-48-3
MF: C8H7NO
MW: 133.15
EINECS: 200-429-5
Melting point: 123-128 °C
Boiling point: 227 °C
Density: 1.1475 g/cm3

Packaging:1 kg/bag, 25 kg/drum

Oxindole (CAS:59-48-3) is an important natural products , which is widely used in various of  chemical fields.

1. Store oxindole in light-proof sealed containers under 25 °C within a dry ventilated area to prevent aerial oxidation of the benzene-fused lactam ring.
2. Limit repeated opening of product packages to avoid moisture absorption and gradual discoloration of solid powder during long-term stock storage.
3. Keep oxindole physically separated from strong oxidants and concentrated alkali to prevent ring-opening hydrolysis and molecular decomposition.

1. The active methylene at the C3 position readily undergoes condensation, alkylation and halogenation reactions for abundant heterocyclic derivatization.
2. The inherent bicyclic lactam skeleton has good binding affinity with multiple biological target proteins for new drug molecular design.
3. Oxindole dissolves well in alcohols, esters and halogenated solvents while maintaining stable reactivity under mild synthetic reaction conditions.

1. Avoid inhaling crystalline dust during weighing and material transfer operations; wear dust masks, splash-proof goggles and chemical-resistant gloves.
2. Oxindole triggers mild irritation on skin, eye surfaces and respiratory mucosa; wash contaminated areas with sufficient running water for at least 15 minutes after contact.
3. Solid residues and waste solvents containing oxindole must be disposed complying with hazardous waste regulations for lactam heterocyclic compounds.