2-Bromophenylhydrazine Hydrochloride CAS 50709-33-6

1. 2-Bromophenylhydrazine hydrochloride is primarily used as a versatile building block in organic and medicinal chemistry for the construction of nitrogen-containing heterocycles and complex molecular architectures . It serves as a key pharmaceutical intermediate in the synthesis of compounds such as quinazoline derivatives, showcasing its role in developing novel therapeutic agents .
2. 2-Bromophenylhydrazine hydrochloride CAS 50709-33-6 is generally utilized in the preparation of azo compounds and as a reagent in organic synthesis . The bromine atom on the phenyl ring offers a handle for further functionalization via metal-catalyzed cross-coupling reactions, enabling the creation of more complex structures .
3. Applications of 2-Bromophenylhydrazine hydrochloride also include its use in the synthesis of pharmaceuticals and agrochemicals . As a hydrazine derivative, 2-Bromophenylhydrazine hydrochloride CAS 50709-33-6 may exhibit biological activity, including potential antitumor properties, though it is primarily used as an intermediate .

1. Store 2-Bromophenylhydrazine hydrochloride in a tightly closed container in a cool, dry, and well-ventilated area away from incompatible substances . Recommended storage conditions include under argon filling, away from moisture , and to minimize dust generation and accumulation .
2. Keep 2-Bromophenylhydrazine hydrochloride away from strong oxidizing agents . 2-Bromophenylhydrazine hydrochloride CAS 50709-33-6 is stable under normal temperatures and pressures .
3. Always 2-Bromophenylhydrazine hydrochloride CAS 50709-33-6 use appropriate personal protective equipment (PPE) including protective gloves, chemical safety goggles, and protective clothing when handling 2-Bromophenylhydrazine hydrochloride to prevent skin, eye, and respiratory contact . Use with adequate ventilation and avoid ingestion and inhalation .

1. Immediately isolate the spill area, use full personal protective equipment, and avoid generating dusty conditions . Ensure adequate ventilation .
2. Sweep up or absorb spilled 2-Bromophenylhydrazine hydrochloride using inert, non-combustible absorbent material, then place the collected material into a suitable clean, dry, closed container for proper disposal according to local, state, and federal environmental regulations . Do not let the product enter drains or waterways .
3. Personnel must 2-Bromophenylhydrazine hydrochloride CAS 50709-33-6 wear suitable PPE, including self-contained breathing apparatus (SCBA) if necessary, during cleanup . Under fire conditions, decomposition products include toxic and irritating fumes such as hydrogen chloride, nitrogen oxides, and carbon monoxide . 2-Bromophenylhydrazine hydrochloride is classified for transport as UN 2811 (Toxic solid, organic, n.o.s., Hazard Class 6.1) .

1. 2-Bromophenylhydrazine hydrochloride is classified with GHS signal word "Danger" . It causes severe skin burns and eye damage (H314) according to GHS classification . 2-Bromophenylhydrazine hydrochloride CAS 50709-33-6 is harmful in contact with skin (H312), harmful if inhaled (H332), and may cause respiratory irritation (H335) .
2. The compound may cause irritation to the digestive tract if swallowed , and its toxicological properties have not been fully investigated . It has a melting point of 189°C or 196-198°C (decomposes) . Hazardous decomposition products include hydrogen chloride, nitrogen oxides, and carbon monoxide .
3. Always 2-Bromophenylhydrazine hydrochloride CAS 50709-33-6 consult the specific Safety Data Sheet (SDS) for 2-Bromophenylhydrazine hydrochloride for complete hazard information, first-aid procedures (P301+P330+P331 for ingestion - do NOT induce vomiting , P303+P361+P353 for skin, P305+P351+P338+P310 for eyes , P304+P340+P310 for inhalation ), and handling instructions. Precautionary statements include P260 (do not breathe dust), P280 (wear protective gloves/eye protection), and P310 (immediately call a poison center/doctor) .