2-Fluorobenzonitrile CAS 394-47-8

1. 2-Fluorobenzonitrile is a key pharmaceutical intermediate used in the synthesis of drugs, including the antidiabetic agent repaglinide and various compounds for treating neurological disorders .
2. 2-Fluorobenzonitrile CAS 394-47-8 serves as a versatile building block in organic synthesis for creating agrochemicals, dyes, pigments, and specialty polymers with enhanced thermal stability .
3. 2-Fluorobenzonitrile is employed in developing fluorescent probes for biological imaging and in materials science for advanced liquid crystals and polymer formulations .

1. Store 2-Fluorobenzonitrile in a tightly sealed container in a cool, dry, well-ventilated area, away from strong oxidizing agents, strong acids, and strong bases .
2. Keep 2-Fluorobenzonitrile CAS 394-47-8 at room temperature (RT) or refrigerated (2-8°C), protected from light and moisture, with the container kept tightly closed when not in use .
3. Handle 2-Fluorobenzonitrile using appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and in a fume hood to avoid breathing dust or vapors and prevent skin and eye contact .

1. Isolate the spill area, eliminate all ignition sources, and avoid dust generation when handling solid or liquid 2-Fluorobenzonitrile .
2. Sweep up solid 2-Fluorobenzonitrile CAS 394-47-8 or contain liquid 2-Fluorobenzonitrile using dry inert absorbent material like sand, and collect into sealed, labeled containers for disposal according to environmental regulations .
3. Prevent spilled 2-Fluorobenzonitrile from entering drains or waterways, as discharge into the environment must be strictly avoided .

1. 2-Fluorobenzonitrile is harmful if swallowed (H302), harmful in contact with skin (H312), and harmful if inhaled (H332) .
2. 2-Fluorobenzonitrile CAS 394-47-8 causes skin irritation (H315), serious eye damage (H318/H319), and may cause respiratory irritation (H335), with GHS signal word "Danger" .
3. 2-Fluorobenzonitrile has a flash point of 73-74°C and combustion produces toxic fumes including hydrogen fluoride, nitrogen oxides, and hydrogen cyanide ; 2-Fluorobenzonitrile is classified for transport as a hazardous substance (UN 3276, Hazard Class 6.1, PG III) .