2-Fluorophenylacetic Acid CAS 451-82-1

1. 2-Fluorophenylacetic acid is widely used in pharmaceutical development as a crucial intermediate for synthesizing anti-inflammatory, analgesic, and other drug compounds .
2. 2-Fluorophenylacetic acid CAS 451-82-1 serves as a chiral derivatizing agent for determining the enantiomeric composition of chiral alcohols and amines by 19F NMR spectroscopy .
3. 2-Fluorophenylacetic acid is utilized in organic synthesis as a building block for creating complex molecules, including thiazolino[3,2-c]pyrimidinediones and enzyme inhibitors .

1. Store 2-Fluorophenylacetic acid in a tightly sealed container in a cool, dry, well-ventilated place, with recommended temperatures ranging from 0-8°C to below 15°C in a dark area .
2. Keep 2-Fluorophenylacetic acid CAS 451-82-1 strictly away from strong oxidizing agents to prevent hazardous decomposition, and protect from light and moisture .
3. Handle 2-Fluorophenylacetic acid using appropriate personal protective equipment including chemical-resistant gloves and safety goggles, and avoid breathing dust or contact with skin and eyes .

1. Isolate the spill area, wear full protective equipment including suitable respirator, and sweep up solid 2-Fluorophenylacetic acid into sealed, labeled containers without creating dust .
2. For small spills, sweep up or absorb 2-Fluorophenylacetic acid CAS 451-82-1 with dry inert material, then place into a suitable clean, dry, closed container for disposal while providing ventilation .
3. Prevent spilled 2-Fluorophenylacetic acid from entering drains or waterways, and dispose of waste according to environmental regulations .

1. 2-Fluorophenylacetic acid causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) with GHS signal word "Warning" .
2. 2-Fluorophenylacetic acid CAS 451-82-1 is not classified as hazardous for transport (DOT, IATA, IMDG), but may cause gastrointestinal irritation if ingested .
3. Combustion of 2-Fluorophenylacetic acid produces toxic fumes including carbon monoxide, carbon dioxide, and hydrogen fluoride, and the compound is incompatible with strong oxidizing agents .