2-Furoyl Chloride CAS 527-69-5

1. 2-Furoyl chloride serves as a key intermediate in synthesizing pharmaceuticals, including the anti-inflammatory prodrug mometasone furoate used for skin disorders and asthma .
2. The compound plays a crucial role in formulating agrochemicals such as herbicides and fungicides for modern agriculture .
3. 2-Furoyl chloride CAS 527-69-5 is utilized in polymer chemistry to create specialty resins with improved thermal stability, and in the flavor industry for its distinctive furan-like aroma .

1. Store 2-Furoyl chloride in a tightly sealed container under inert gas in a cool, dry place, as it is moisture sensitive and decomposes in contact with water .
2. Keep 2-Furoyl chloride CAS 527-69-5 strictly away from strong oxidizing agents, strong bases, and alcohols due to incompatibility and risk of violent reactions .
3. Handle 2-Furoyl chloride using appropriate personal protective equipment including chemical-resistant gloves, face shield, and in a fume hood, as it is corrosive and a lachrymator (causes eye burns and tearing) .

1. Isolate the spill area immediately, eliminate all ignition sources, and wear full protective equipment including self-contained breathing apparatus before handling 2-Furoyl chloride .
2. Contain liquid 2-Furoyl chloride CAS 527-69-5 using dry inert absorbent material like sand, collect using non-sparking tools into sealed, labeled corrosion-resistant containers for disposal .
3. Personnel cleaning 2-Furoyl chloride spills must prevent entry into drains or waterways, as discharge into the environment must be avoided, and dispose of waste through a licensed chemical destruction facility .

1. 2-Furoyl chloride is classified with GHS signal word "Danger" as a corrosive substance (H314, H318) causing severe skin burns and serious eye damage, and is harmful if swallowed (H302, oral LD50 rat: 616 mg/kg) .
2. 2-Furoyl chloride CAS 527-69-5 may cause genetic defects (H341) and is a combustible liquid (H227) with a flash point of 85°C .
3. Thermal decomposition of 2-Furoyl chloride produces toxic fumes including carbon monoxide, carbon dioxide, and hydrogen chloride gas; the compound is classified for transport as a corrosive liquid (UN 3265, Hazard Class 8, Packing Group II) .