3-Bromobenzotrifluoride CAS 401-78-5

1. 3-Bromobenzotrifluoride CAS 401-78-5 serves as a building block for synthesizing calcium channel inhibitors used to treat inflammatory and neuropathic pain .
2. 3-Bromobenzotrifluoride participates in palladium-catalyzed cross-coupling reactions to form aryl triflates and is used in the production of pharmaceuticals like the anti-obesity drug fenfluramine .
3. 3-Bromobenzotrifluoride acts as a versatile reagent in organic synthesis and finds applications as a solvent in chromatography and as a probe in NMR spectroscopy .

1. Store 3-Bromobenzotrifluoride CAS 401-78-5 in a tightly sealed container in a cool, dry, well-ventilated flammable liquids storage area, as it is a combustible liquid .
2. Keep 3-Bromobenzotrifluoride away from heat, sparks, open flames, and incompatible materials including strong oxidizing agents and bases .
3. Handle 3-Bromobenzotrifluoride using appropriate personal protective equipment including chemical-resistant gloves (fluorinated rubber), safety goggles with face shield, and in a fume hood to avoid breathing vapors and prevent skin and eye contact .

1. Isolate the spill area, eliminate all ignition sources, and contain liquid 3-Bromobenzotrifluoride CAS 401-78-5 using non-combustible absorbent material like dry sand or earth, preventing entry into drains or waterways .
2. Collect absorbed 3-Bromobenzotrifluoride using non-sparking tools into sealed, labeled containers for disposal according to hazardous material regulations .
3. Personnel cleaning 3-Bromobenzotrifluoride spills must wear full protective equipment including self-contained breathing apparatus, as vapors are heavier than air and may accumulate to form explosive concentrations .

1. 3-Bromobenzotrifluoride CAS 401-78-5 is a flammable liquid and vapor (H226, flash point 43°C/110°F) and is classified with GHS signal word "Warning" .
2. 3-Bromobenzotrifluoride causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) .
3. 3-Bromobenzotrifluoride is classified for transport as a flammable liquid (UN 1993, Hazard Class 3, Packing Group III), and combustion produces toxic fumes including carbon monoxide, hydrogen fluoride, and hydrogen bromide .