3-Chlorobenzoic Acid CAS 535-80-8

1. 3-Chlorobenzoic acid is used as an intermediate in manufacturing fungicides, dyes, and pharmaceuticals, and as a preservative for glues and paints . It serves as a crucial building block in organic synthesis .
2. The compound is widely utilized in scientific research, particularly in biodegradation studies as a model substrate for chlorinated aromatic compounds and in environmental remediation research . 3-Chlorobenzoic acid CAS 535-80-8 has demonstrated antifungal activity against *Aspergillus* strains .
3. Applications of 3-Chlorobenzoic acid also include its use in the preparation of various chemical compounds through oxidation, reduction, and substitution reactions .

1. Store 3-Chlorobenzoic acid in a tightly sealed container in a cool, dry, and well-ventilated place, protected from light . Recommended storage temperatures include ambient conditions, a cool, dark place, or at -20°C for long-term stability .
2. Keep 3-Chlorobenzoic acid away from strong oxidizing agents and strong bases, as these are incompatible materials . Avoid conditions that generate dust or aerosols .
3. Always use 3-Chlorobenzoic acid CAS 535-80-8 appropriate personal protective equipment (PPE) including protective gloves (e.g., nitrile), safety goggles, and protective clothing; wash hands thoroughly after handling and ensure adequate ventilation when handling 3-Chlorobenzoic acid .

1. Immediately isolate the spill area, avoid dust formation, and contain 3-Chlorobenzoic acid using inert, non-combustible absorbent material; prevent material from entering drains or waterways .
2. Carefully sweep up the spilled 3-Chlorobenzoic acid solid using clean, non-sparking tools and place the collected material into a sealed, labeled chemical waste container for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must 3-Chlorobenzoic acid CAS 535-80-8 wear suitable PPE during cleanup; under fire conditions, toxic fumes including carbon monoxide and hydrogen chloride may be released, requiring full protective gear including self-contained breathing apparatus (SCBA) .

1. 3-Chlorobenzoic acid is classified as an irritant (GHS signal word "Warning"), causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) . 3-Chlorobenzoic acid CAS 535-80-8 is not classified as dangerous goods for transport by some regulations .
2. 3-Chlorobenzoic acid is combustible with a flash point of 150°C and a melting point range of 153-160°C . Its thermal decomposition or combustion produces toxic and irritating fumes including carbon monoxide and hydrogen chloride gas . Solubility in water is low (0.45 g/l) .
3. Always consult the specific Safety Data Sheet (SDS) for 3-Chlorobenzoic acid for complete hazard information, first-aid procedures (P305+P351+P338 for eyes, P302+P352 for skin, P301+P330+P331 for ingestion), and handling instructions; precautionary statements include P261 (avoid breathing dust), P271 (use only in well-ventilated area), and P280 (wear protective gloves/eye protection) .