3-Hydroxybenzaldehyde CAS 100-83-4

1. 3-Hydroxybenzaldehyde is a key intermediate in pharmaceutical development, particularly for synthesizing anti-inflammatory and analgesic drugs . It serves as a versatile building block in organic synthesis to produce more complex molecules like monastrol and (-)-Quinocarcin .
2. 3-Hydroxybenzaldehyde CAS 100-83-4 is used in the flavor and fragrance industry to create aromatic compounds for perfumes and flavorings . It is also employed in the development of dyes, fungicides, and photographic emulsion chemicals .
3. Applications of 3-Hydroxybenzaldehyde include its use in material science for developing polymers and coatings, as well as in analytical chemistry as a reagent for detecting other substances and as an ionophore in PVC membrane sensors .

1. Store 3-Hydroxybenzaldehyde in a tightly sealed container in a cool, dry, well-ventilated area away from incompatible substances like strong oxidizing agents . Recommended storage temperatures vary from refrigeration (0-8 °C) to ambient conditions, with sensitive solutions requiring storage at -80°C under inert gas .
2. Keep 3-Hydroxybenzaldehyde away from strong oxidizing agents, as it is incompatible . 3-Hydroxybenzaldehyde CAS 100-83-4 is sensitive to air and light, and prolonged exposure may cause product degradation .
3. Always use appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing; ensure adequate ventilation and avoid breathing dust when handling 3-Hydroxybenzaldehyde .

1. Immediately isolate the spill area, eliminate all ignition sources, and contain 3-Hydroxybenzaldehyde using inert, non-combustible absorbent material; avoid generating dusty conditions .
2. Carefully sweep up the spilled solid using clean, non-sparking tools and place the collected material into a sealed, labeled chemical waste container for proper disposal according to local, state, and federal environmental regulations .
3. Personnel 3-Hydroxybenzaldehyde CAS 100-83-4 must wear suitable PPE during cleanup; 3-Hydroxybenzaldehyde is harmful to aquatic life with long-lasting effects (WGK 2-3) and should be prevented from entering drains or waterways . Under fire conditions, irritating and toxic gases may be generated, requiring self-contained breathing apparatus .

1. 3-Hydroxybenzaldehyde is classified as an irritant (GHS signal word "Warning"), causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335) . It is harmful if swallowed (H302) and may cause gastrointestinal irritation with nausea and vomiting .
2. 3-Hydroxybenzaldehyde is combustible with a flash point of 99°C . Its thermal decomposition or combustion produces toxic and irritating fumes including carbon monoxide and carbon dioxide . It is listed as a mutagen (RTECS Class) and has a pKa of 9.24 .
3. Always consult 3-Hydroxybenzaldehyde CAS 100-83-4 the specific Safety Data Sheet (SDS) for 3-Hydroxybenzaldehyde for complete hazard information, first-aid procedures (P305+P351+P338 for eyes, P301+P312+P330 for ingestion), and handling instructions; precautionary statements include P261 (avoid breathing dust), P273 (avoid release to environment), and P280 (wear protective gloves/eye protection) .