3-Fluorotoluene CAS 352-70-5

1. 3-Fluorotoluene is primarily used as a key intermediate and building block in the synthesis of pharmaceuticals and agrochemicals, where the fluorine atom enhances drug efficacy and metabolic stability . It is a critical compound for developing drug molecules with improved bioavailability .
2. 3-Fluorotoluene CAS 352-70-5 is employed in material science for developing advanced materials such as polymers and coatings, and it also acts as a solvent in various chemical reactions . It has been used in the gas-phase selective synthesis of 3-fluorobenzaldehyde .
3. Applications of 3-Fluorotoluene include its use in environmental monitoring as an analytical standard for detecting fluorinated compounds, as well as in biochemical research to study enzyme-catalyzed reactions involving fluorinated compounds .

1. Store 3-Fluorotoluene in a tightly sealed container in a cool, dry, and well-ventilated place away from heat, sparks, and open flames; recommended storage is at room temperature (RT) or in a cool, dark place . Keep the container tightly closed and upright to prevent leakage .
2. Keep 3-Fluorotoluene strictly away from strong oxidizing agents, as 3-Fluorotoluene CAS 352-70-5 is incompatible and can cause hazardous reactions . It is also incompatible with reducing agents, amines, and alkali metals .
3. Always use appropriate personal protective equipment (PPE) including chemical-resistant gloves (fluorinated rubber), safety goggles, face shield, and protective clothing . Use only with explosion-proof equipment and adequate ventilation, and take measures to prevent the build-up of electrostatic charge .

1. Immediately isolate the spill area (at least 50 meters in all directions), eliminate all ignition sources, and ensure adequate ventilation . Contain 3-Fluorotoluene using inert, non-combustible absorbent material (e.g., dry sand) and prevent entry into drains or waterways .
2. Carefully collect 3-Fluorotoluene CAS 352-70-5 using an electrically protected vacuum cleaner, by wet-brushing, or with non-sparking tools, and place it into a sealed, labeled chemical waste container for proper disposal according to local regulations . For large spills, dike far ahead of the liquid spill .
3. Personnel must wear full chemical-protective equipment including self-contained breathing apparatus (SCBA) during cleanup . 3-Fluorotoluene is classified for transport (UN2388, Hazard Class 3, PG II) and requires hazardous waste disposal .

1. 3-Fluorotoluene is classified as a highly flammable liquid and vapor (H225, Danger) with a flash point of 9°C (48-49°F) . It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) .
2. 3-Fluorotoluene is harmful if swallowed, inhaled, or absorbed through the skin; its combustion or thermal decomposition produces toxic and corrosive fumes including carbon oxides and hydrogen fluoride . Prolonged exposure may result in systemic toxic effects .
3. Always consult 3-Fluorotoluene CAS 352-70-5 the specific Safety Data Sheet (SDS) for 3-Fluorotoluene for complete hazard information, first-aid procedures (P303+P361+P353 for skin, P305+P351+P338 for eyes, P301+P330+P331 for ingestion), and handling instructions. Precautionary statements include P210 (keep away from heat/sparks/open flames), P233 (keep container tightly closed), P240 (ground/bond container), P261 (avoid breathing vapors), and P280 (wear protective gloves/eye protection) .