Products Description
Product Name: 4-Fluorophenylacetonitrile
CAS: 459-22-3
EINECS: 207-286-8
Melting point: 86°C
Boiling point: 119-120 °C
Density: 1.126 g/mL
Refractive index: n20/D 1.5002
Specification
| Items | Specifications |
| Appearance | Colorless and transparent liquid |
| Purity | ≥99% |
| Water | ≤0.1% |
Application
1. 4-Fluorophenylacetonitrile CAS 459-22-3 is a key building block in pharmaceutical research for synthesizing central nervous system, oncology, and anti-inflammatory drug candidates .
2. 4-Fluorophenylacetonitrile serves as a versatile precursor for preparing fluorinated heterocycles like indoles, quinolines, and pyrimidines with enhanced biological activity .
3. 4-Fluorophenylacetonitrile is used to synthesize daidzein analogs with anti-influenza activity and benzothiazole sulfonamides exhibiting anti-inflammatory properties .
Storage and Precautions
1. Store 4-Fluorophenylacetonitrile CAS 459-22-3 in a tightly sealed container in a cool, dry, well-ventilated area away from incompatible substances .
2. Keep 4-Fluorophenylacetonitrile strictly separated from strong oxidizing agents to prevent hazardous decomposition .
3. Handle 4-Fluorophenylacetonitrile using appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and in a fume hood to avoid breathing vapors or dust .
Emergency response to leakage
1. Isolate the spill 4-Fluorophenylacetonitrile CAS 459-22-3 area, eliminate ignition sources, and contain liquid 4-Fluorophenylacetonitrile using dry inert absorbent material like sand, preventing entry into drains or waterways .
2. Sweep up or collect absorbed 4-Fluorophenylacetonitrile into sealed, labeled containers for disposal according to environmental regulations .
3. Personnel cleaning 4-Fluorophenylacetonitrile spills must wear suitable protective equipment and ensure adequate ventilation during cleanup .
Safety Information
1. 4-Fluorophenylacetonitrile CAS 459-22-3 is harmful if swallowed (H302), in contact with skin (H312), or if inhaled (H332), and causes skin and serious eye irritation.
2. 4-Fluorophenylacetonitrile may cause respiratory irritation (H335) and is classified for transport as a toxic liquid (UN 3276, Hazard Class 6.1, Packing Group III) .
3. 4-Fluorophenylacetonitrile has a flash point of 108°C and combustion produces toxic fumes including carbon monoxide, nitrogen oxides, and hydrogen fluoride .
Recommended Products
| Items | Product Name |
| 1 | 4-Butylacetophenone CAS 37920-25-5 |
| 2 | Butyryl Chloride CAS 141-75-3 |
| 3 | 4-Chlorobenzenesulfonamide CAS 98-64-6 |
| 4 | 4-Fluoroacetophenone CAS 403-42-9 |
| 5 | 4-Iodoanisole CAS 696-62-8 |
| 6 | P-Anisidine/p-Methoxyaniline/4-Methoxyaniline CAS 104-94-9 |
| 7 | 4-Fluorobenzyl chloride CAS 352-11-4 |
| 8 | p-Phenylenediamine dihydrochloride CAS 624-18-0 |
| 9 | 1 4-Dicyanobenzene CAS 623-26-7 |
| 10 | If you want to need more information,welcome to contact us at any time.
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Packaging
Transportation & Payment
About Transportation
Depending on the requirements of our clients, we can give a variety of transportation options.
For smaller orders, we offer air shipping or international courier services like FedEx, DHL, TNT, EMS, and numerous other unique lines of international transit.
We can transport by sea to a specified port for bigger amounts.
Additionally, we can offer unique services based on the requirements of our clients and the characteristics of their goods.
* We can offer a range of payment options to our clients.
* When the sum is modest, clients typically pay with PayPal, Western Union, Alibaba, and other similar services.
* When the sum is significant, clients typically pay with T/T, L/C at sight, Alibaba, and so on.
* Furthermore, an increasing number of consumers will use Alipay or WeChat Pay to make payments.
FAQ
1
May I get any sample from you?
Re: Yes, of course, we'd like to provide sample to you according to your demands.
2
What is your MOQ?
Re: Usually our MOQ is 1 kg, but sometimes it is also flexible and depends on different products.
3
How long I can get my goods after payment?
Re: If shipped by couriers or air, it usually cost 5-10 days.
If shipped by sea, it usually cost 3-40 days, which depends on your destination.
4
Do you have any after-sales service?
Re: Yes, we will inform you progress of the order, such as product preparation, declaration, transportation follow-up, customs clearance assistance, technical guidance, etc.
Contact Us
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