4-Chlorobenzenesulfonamide CAS 98-64-6

1. 4-Chlorobenzenesulfonamide demonstrates significant anticonvulsant activity in animal models, proving effective against both maximal electroshock and chemically induced seizures .
2. 4-Chlorobenzenesulfonamide CAS 98-64-6 acts as an enzyme inhibitor, targeting carbonic anhydrase isozymes with high potency and serving as a scaffold for novel glycine transporter 1 (GlyT1) inhibitors .
3. 4-Chlorobenzenesulfonamide is used as a versatile intermediate in the synthesis of pharmaceuticals, including potential PET imaging agents for neuroinflammation, as well as in dyes, insecticides, and the chloramine industry .

1. Store 4-Chlorobenzenesulfonamide in a tightly sealed container in a cool, dry, and well-ventilated area, as it is stable under normal conditions .
2. Keep 4-Chlorobenzenesulfonamide CAS 98-64-6 away from strong bases to prevent hazardous reactions and protect containers from physical damage .
3. Handle 4-Chlorobenzenesulfonamide using appropriate personal protective equipment including nitrile gloves, safety goggles, and in a fume hood to avoid dust generation and contact with skin and eyes .

1. Isolate the spill 4-Chlorobenzenesulfonamide CAS 98-64-6 area, avoid dust formation, and sweep up solid 4-Chlorobenzenesulfonamide using clean methods into sealed, labeled containers for disposal .
2. Prevent spilled 4-Chlorobenzenesulfonamide from entering drains or waterways, and ensure adequate ventilation during cleanup operations .
3. Personnel cleaning 4-Chlorobenzenesulfonamide spills must wear suitable protective equipment including dust masks and dispose of waste according to federal, state, and local environmental regulations .

1. 4-Chlorobenzenesulfonamide causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) with GHS signal word "Warning" .
2. 4-Chlorobenzenesulfonamide CAS 98-64-6 has an oral LD50 of 2700 mg/kg in mice and an NFPA health rating of 1 (exposure would cause irritation with minor residual injury) .
3. Combustion of 4-Chlorobenzenesulfonamide produces toxic fumes including carbon oxides, nitrogen oxides, sulfur oxides, and hydrogen chloride gas .