Acetoxyacetyl Chloride CAS 13831-31-7

1. Acetoxyacetyl chloride is widely utilized as a key intermediate in the synthesis of pharmaceuticals, enhancing drug development processes, and as a reagent for preparing esters and other derivatives in organic synthesis .
2. Acetoxyacetyl chloride CAS 13831-31-7 serves as a crucial building block in the synthesis of new β-lactam derivatives, contributing to advances in medicinal chemistry and the synthesis of natural products .
3. Applications of Acetoxyacetyl chloride also include its use in the production of agrochemicals (herbicides and pesticides) and in polymer chemistry for developing specialty polymers with tailored properties for coatings and adhesives .

1. Store Acetoxyacetyl chloride in a tightly sealed container under an inert gas (e.g., argon) in a cool, dry, and well-ventilated place; recommended storage temperatures vary from refrigeration (2-8 °C) to a cool, dark place below 15°C .
2. Keep Acetoxyacetyl chloride strictly away from moisture, strong oxidizing agents, strong bases, and alcohols, as it reacts violently with water and is incompatible with these materials .
3. Always Acetoxyacetyl chloride CAS 13831-31-7 use appropriate personal protective equipment (PPE) including tightly fitting safety goggles, face shield, chemical-resistant gloves, and protective clothing; handle only in a fume hood to avoid breathing vapors, mist, or gas .

1. Immediately isolate the spill area, eliminate all ignition sources, and ensure adequate ventilation; contain Acetoxyacetyl chloride using dry, inert, non-combustible absorbent material and absolutely avoid contact with water .
2. Carefully collect Acetoxyacetyl chloride CAS 13831-31-7 using an electrically protected vacuum cleaner or by wet-brushing, and place it into a sealed, corrosion-resistant chemical waste container for disposal according to local regulations .
3. Personnel must wear full chemical-protective equipment including self-contained breathing apparatus (SCBA) if necessary during cleanup; prevent entry into drains or waterways and dispose of all waste according to hazardous material regulations (UN3265, Hazard Class 8, PG II) .

1. Acetoxyacetyl chloride is classified as a corrosive substance (GHS05, Danger) causing severe skin burns and serious eye damage (H314/H318), is a combustible liquid (H227), and may be corrosive to metals (H290) .
2. Acetoxyacetyl chloride may cause respiratory irritation (H335); it reacts violently with water, and its thermal decomposition or combustion produces toxic and corrosive fumes including carbon oxides and hydrogen chloride gas .
3. Always Acetoxyacetyl chloride CAS 13831-31-7 consult the specific Safety Data Sheet (SDS) for Acetoxyacetyl chloride for complete hazard information, first-aid procedures (P301+P330+P331 for ingestion, P303+P361+P353 for skin, P305+P351+P338 for eyes), and handling instructions; precautionary statements include P260 (do not breathe vapors), P280 (wear protective gloves/eye protection), and P403+P235 (store in well-ventilated place, keep cool) .