Butyl Isocyanate CAS 111-36-4

1. Butyl isocyanate is an important raw material and intermediate for synthesizing benzimidazole fungicides, sulfonylurea herbicides, and various pharmaceutical products .
2. Butyl isocyanate CAS 111-36-4 is involved in the production of sulfonylurea derivatives used in diabetes treatment and acts as a catalyst in the synthesis of herbicides for agriculture .
3. Butyl isocyanate is used in the manufacture of insecticides and dyestuffs, serving as a versatile building block in the chemical industry .

1. Store Butyl isocyanate in a tightly sealed container under inert gas in a cool, dry, well-ventilated area (2-8°C recommended), as Butyl isocyanate is moisture sensitive and reacts with water .
2. Keep Butyl isocyanate CAS 111-36-4 strictly away from heat, sparks, open flames, strong oxidants, acids, and bases due to its high flammability and violent reaction potential .
3. Handle Butyl isocyanate using appropriate personal protective equipment including chemical-resistant gloves and safety goggles, as Butyl isocyanate is fatal if inhaled, causes severe skin burns, and may cause allergic skin reactions .

1. Immediately isolate the spill area (200 ft for small spills, 1000 ft for large spills) and wear full protective equipment including self-contained breathing apparatus before handling Butyl isocyanate .
2. Contain liquid Butyl isocyanate CAS 111-36-4 using dry inert non-combustible absorbent material like sand, collect using non-sparking tools into sealed, labeled containers for disposal, and prevent entry into drains or waterways .
3. Personnel cleaning Butyl isocyanate spills must avoid water contact, use explosion-proof equipment, and dispose of waste through a licensed hazardous waste facility .

1. Butyl isocyanate is classified with GHS signal word "Danger" as a highly flammable liquid (flash point 18°C) and vapor (H225) that is fatal if inhaled (H330, LC50 rat 59 mg/m³) and causes severe skin burns and eye damage (H314, H318) .
2. Butyl isocyanate CAS 111-36-4 is harmful if swallowed (oral LD50 rat 360 mg/kg) and may cause allergic skin reactions (H317) and specific target organ toxicity (H370) .
3. Butyl isocyanate is classified for transport as a poison inhalation hazard (UN 2485, Hazard Class 6.1/3, Packing Group I) and thermal decomposition produces toxic fumes including nitrogen oxides and hydrogen cyanide .