Methyl Propiolate CAS 922-67-8

1. Methyl propiolate CAS 922-67-8 is used in the synthesis of polysubstituted 3-arylaminoacrylate and tetrahydropyrimidin-2-one derivatives .
2. Methyl propiolate serves as a thiol derivatizing agent for capillary electrophoresis applications .
3. Methyl propiolate participates in free-radical additions of diselenides and conjugate addition reactions catalyzed by fluoride .

1. Store Methyl propiolate CAS 922-67-8 under inert gas (argon filling) in a cool, dry place at 2-8°C, protected from light .
2. Keep Methyl propiolate strictly away from strong oxidizing agents, acids, and bases due to incompatibility .
3. Handle Methyl propiolate using appropriate personal protective equipment including chemical-resistant gloves and safety goggles, and use in a well-ventilated area or fume hood .

1. Isolate the spill area, eliminate all ignition sources, and contain liquid Methyl propiolate using non-combustible absorbent material like sand, preventing entry into drains or waterways .
2. Collect absorbed Methyl propiolate using non-sparking tools into sealed, labeled containers for disposal according to environmental regulations .
3. Personnel cleaning Methyl propiolate spills must wear full protective equipment including self-contained breathing apparatus, as Methyl propiolate is highly flammable.

1. Methyl propiolate CAS 922-67-8 is highly flammable (flash point 16°C) and is classified with GHS signal word "Danger" and hazard statements.
2. Methyl propiolate causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) .
3. Methyl propiolate has a boiling point of 103-105°C, density of 0.945 g/mL, and is insoluble in water .