2-Bromodibenzofuran CAS 87-76-0

1. 2-Bromodibenzofuran CAS 87-76-0 is primarily used as a versatile synthetic intermediate in organic chemistry, particularly for constructing complex molecules via metal-catalyzed cross-coupling reactions such as Suzuki, Stille, and Negishi couplings .
2. 2-Bromodibenzofuran serves as a key building block in materials science for developing advanced organic semiconductors, including those used in OLEDs and OFETs, where its rigid, planar dibenzofuran core enhances charge transport properties and molecular stability .
3. 2-Bromodibenzofuran is employed in medicinal chemistry for the synthesis of biologically active compound libraries and pharmaceutical intermediates targeting various therapeutic areas .
4. Researchers utilize 2-Bromodibenzofuran as a precursor for creating fluorescent probes for biological imaging, in environmental studies examining pollutant degradation, and as a reagent in Friedel-Crafts acylation reactions .

1. 2-Bromodibenzofuran CAS 87-76-0 must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light, with storage temperatures ranging from room temperature (in a cool, dark place, <15°C) to -20°C for long-term stability .
2. 2-Bromodibenzofuran should be kept under inert gas (such as nitrogen) to prevent oxidation, stored away from heat sources and incompatible materials such as strong oxidizing agents, strong acids, and strong bases .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling 2-Bromodibenzofuran, as it causes serious eye irritation and is harmful if swallowed (H302, H319) .
4. Avoid formation of dust and aerosols, ensure adequate ventilation in work areas (preferably a chemical fume hood), wash thoroughly after handling, and avoid release to the environment as it may cause long-lasting harmful effects to aquatic life (H413) .

1. Isolate the spill area, ensure adequate ventilation, and avoid dust formation when 2-Bromodibenzofuran CAS 87-76-0 is released, wearing full personal protective equipment including chemical impermeable gloves, safety goggles, face protection, and respiratory protection if necessary .
2. Collect 2-Bromodibenzofuran by sweeping or vacuuming without creating dust, using spark-proof tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure, and prevent the product from entering drains or water courses due to its potential aquatic toxicity .
4. Dispose of collected 2-Bromodibenzofuran material according to local, state, and federal environmental regulations, preferably through licensed chemical destruction or controlled incineration, following precautionary statement P501 .

1. 2-Bromodibenzofuran CAS 87-76-0 is not classified as highly flammable but may decompose under fire conditions, with a boiling point of approximately 220°C at 40 mmHg and 343.8°C at 760 mmHg, emitting toxic fumes when involved in a fire .
2. Use water spray, dry chemical powder, alcohol-resistant foam, or carbon dioxide to extinguish fires involving the product, avoiding straight water streams that may spread the fire .
3. Firefighters should wear self-contained breathing apparatus and full protective gear when handling burning 2-Bromodibenzofuran due to hazardous decomposition gases including 2-Bromodibenzofuran carbon monoxide, carbon dioxide, nitrogen oxides (NOx), and hydrogen bromide .
4. During combustion, may emit irritant and toxic fumes; move containers from the fire area if safe to do so, cool exposed containers with water spray, contain fire runoff to prevent environmental contamination, and collect contaminated fire extinguishing water separately .