4-tert-Butylphenyl-acetonitrile CAS 3288-99-1

1. 4-tert-Butylphenyl-acetonitrile is a key intermediate in the synthesis of pharmaceutical compounds, including the antifungal agent butenafine hydrochloride and other bioactive molecules .
2. 4-tert-Butylphenyl-acetonitrile CAS 3288-99-1 serves as a versatile building block in organic synthesis for the preparation of substituted acetonitriles, which are further converted to carboxylic acids, amines, and other functional groups via hydrolysis, reduction, or alkylation reactions .
3. 4-tert-Butylphenyl-acetonitrile is employed in the synthesis of agrochemicals and specialty chemicals, including photoinitiators and stabilizers for polymer formulations .
4. Researchers utilize 4-tert-Butylphenyl-acetonitrile CAS 3288-99-1 as a reference standard in analytical chemistry and as a precursor for the preparation of fragrance components and fine chemical intermediates .

1. 4-tert-Butylphenyl-acetonitrile must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at 2-8°C or at room temperature in a cool, dark place .
2. 4-tert-Butylphenyl-acetonitrile CAS 3288-99-1 is classified with GHS hazard statements H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H332 (Harmful if inhaled), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition; wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when 4-tert-Butylphenyl-acetonitrile is released .
2. Collect 4-tert-Butylphenyl-acetonitrile CAS 3288-99-1 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. 4-tert-Butylphenyl-acetonitrile is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as 4-tert-Butylphenyl-acetonitrile CAS 3288-99-1 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning 4-tert-Butylphenyl-acetonitrile due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .