N-(4-Methylphenyl)-3-oxobutanamide CAS 2415-85-2

1. N-(4-Methylphenyl)-3-oxobutanamide CAS 2415-85-2 (also known as acetoacet-p-toluidide) is a key intermediate in the synthesis of azo pigments, particularly Pigment Yellow 74 and other acetoacetarylide pigments, widely used in printing inks, paints, and plastics for their excellent color strength and fastness properties .
2. N-(4-Methylphenyl)-3-oxobutanamide serves as a coupling component in the preparation of organic pigments through diazotization reactions, contributing to high-performance colorants with good heat and solvent resistance .
3. In the dye and pigment industry, N-(4-methylphenyl)-3-oxobutanamide is utilized as a building block for manufacturing various acetoacetic amide derivatives and specialty colorants .
4. N-(4-Methylphenyl)-3-oxobutanamide is also employed in chemical research and development for the synthesis of other organic compounds, including pharmaceutical intermediates and heterocyclic systems .

1. N-(4-Methylphenyl)-3-oxobutanamide must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at room temperature in a cool, dark place .
2. N-(4-Methylphenyl)-3-oxobutanamide is stable under recommended storage conditions when kept away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas and avoiding formation of dust and aerosols .
4. N-(4-Methylphenyl)-3-oxobutanamide may cause skin and eye irritation; wash thoroughly after handling and use appropriate dust masks if airborne particles are generated .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when N-(4-Methylphenyl)-3-oxobutanamide is released .
2. Collect N-(4-Methylphenyl)-3-oxobutanamide by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. N-(4-Methylphenyl)-3-oxobutanamide is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as N-(4-Methylphenyl)-3-oxobutanamide may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning N-(4-Methylphenyl)-3-oxobutanamide due to hazardous decomposition gases generated by thermal decomposition .