Borneol Oil CAS 6627-72-1

1. Borneol oil CAS 6627-72-1 is a component of certain aromatic plant essential oils, with the essential oil from *Cinnamomum camphora* chvar. *Borneol* containing 18.2% v/v borneol as a by-product of natural crystalline borneol production .
2. Borneol oil has demonstrated analgesic potential in preclinical studies, significantly reducing acetic acid-induced writhing in mice with a strong dose-response relationship (r = -0.9006) and decreasing serum pain-related mediators such as prostaglandin E2 (PGE2) and TRPM8 .
3. In traditional Chinese medicine, borneol is used to relieve symptoms of anxiety, fatigue, and insomnia, induce anesthesia and analgesia for abdominal pain and burns, treat cardiovascular and cerebrovascular diseases, and is recognized as a GRAS (Generally Recognized as Safe) food flavor by the FDA .
4. The molecular targets of borneol include GABAA, TRPV3, TRPM8, and TRPA1 channels, and it has been studied for its neuroprotective, antiapoptotic, and antioxidative effects .

1. Borneol oil CAS 6627-72-1 and its solid components must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from direct sunlight and sources of ignition .
2. For long-term stability, powder forms should be stored at -20°C (stable for up to 3 years) or at 4°C (stable for up to 2 years); solutions should be stored at -20°C for up to 1 month or at -80°C for up to 6 months .
3. Personnel Borneol oil must wear chemical-resistant gloves, safety goggles with side-shields, and impervious protective clothing when handling this substance, avoiding inhalation, dust and aerosol formation, and ensuring adequate ventilation .
4. Borneol is classified as a flammable solid (UN 1312, Class 4.1) with NFPA health and flammability ratings of 2, indicating moderate hazard; it is incompatible with strong oxidizing agents, strong acids/alkalis, and strong reducing agents .

1. Isolate the spill area immediately for at least 25 meters (75 feet) in all directions, eliminate all ignition sources (no smoking, flares, sparks, or flames), and wear full personal protective equipment including positive pressure self-contained breathing apparatus (SCBA) .
2. For small dry spills, collect the spilled product with a clean shovel without creating dust and place into clean, dry containers, covering loosely; for large spills, wet down with water and dike for later disposal .
3. Avoid creating dust clouds during cleanup; absorb solutions with finely-powdered liquid-binding materials such as diatomite or universal binders, and decontaminate surfaces by scrubbing with alcohol .
4. Prevent Borneol oil from entering drains, water courses, or sewers, as runoff from fire control or dilution water may cause environmental contamination; dispose of collected material in accordance with local, state, and federal regulations .

1. Borneol is a combustible/flammable solid (UN 1312, Class 4.1) with NFPA flammability rating of 2; it may be ignited by friction, heat, sparks, or flames, and powders, dusts, or shavings may explode or burn with explosive violence .
2. For small fires, use dry chemical powder, CO2, sand, earth, or water spray; for large fires, use water spray, fog, or regular foam; do NOT use a direct water jet as Borneol oil may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning Borneol oil due to hazardous decomposition gases and the potential for irritating and/or toxic fumes .
4. Cool exposed containers with flooding quantities of water until well after fire is out; if safe to do so, move containers away from the fire area; contain fire runoff to prevent environmental contamination .