Grape Seed Oil CAS 8024-22-4

1. Grape seed oil CAS 8024-22-4 is rich in bioactive compounds, primarily linoleic acid (58-78%), vitamin E (tocopherols and tocotrienols), and phytosterols, along with phenolic compounds like catechins (414 mg) and epicatechins (130.4 mg), which contribute to its therapeutic potential .
2. Research Grape Seed Oil indicates grape seed oil possesses significant anti-inflammatory and antioxidant properties, demonstrated by its ability to reduce paw edema in animal models and modulate serum levels of glutathione (GSH) and malondialdehyde (MDA) .
3. In pharmaceutical technology, grape seed oil is utilized as a key component in advanced drug delivery systems, such as microemulsions and self-nanoemulsifying drug delivery systems (SNEDDS), to improve the skin penetration and bioavailability of drugs like resveratrol .
4. Researchers also employ Grape Seed Oil as a reference or raw material in studies exploring its nutraceutical potential in conditions related to oxidative stress, inflammation, obesity, and metabolic alterations .

1. Grape seed oil CAS 8024-22-4 must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, away from direct sunlight and sources of ignition . For long-term stability, storage at -20°C (for powder forms) or -80°C (in solvent) is recommended .
2. Grape Seed Oil is susceptible to oxidation; exposure to light and room temperature (22°C) can lead to a significant increase in peroxide value (up to 484 meq O2/kg oil), indicating the formation of primary oxidation products .
3. Refrigeration at 4°C in the dark is the least intrusive storage method, as it preserves the stability of the oil and its antioxidant tocotrienols (α-, γ-, δ-) and tocopherols (α-, γ-), with practically no decomposition observed during storage .
4. Personnel should avoid breathing vapors, mists, or dust, and prevent skin and eye contact. Use only in areas with appropriate exhaust ventilation .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment (including safety goggles, protective gloves, and suitable respirator) . Evacuate personnel to safe areas .
2. Absorb Grape Seed Oil with finely-powdered liquid-binding material (such as diatomite or universal binders) . Try to prevent further leakage or spillage .
3. Keep the product away from drains, water courses, or the soil, as it is very toxic to aquatic life with long-lasting effects (H410) .
4. Decontaminate surfaces and equipment by scrubbing with alcohol and dispose of contaminated material in accordance with local, state, and federal environmental regulations .

1. During combustion, grape seed oil may decompose and emit irritant and potentially toxic fumes, including carbon oxides .
2. Use Grape Seed Oil water spray, dry chemical, foam, and carbon dioxide fire extinguishers to extinguish fires involving the product .
3. Firefighters should wear self-contained breathing apparatus and full protective clothing when handling burning grape seed oil .
4. Prevent runoff from fire control or dilution water from entering drains or water courses, as it may cause pollution .