Gamma Linolenic Acid CAS 506-26-3

1. Gamma-linolenic acid CAS 506-26-3 is a biologically active omega-6 polyunsaturated fatty acid primarily used in research for its anti-inflammatory, immunomodulatory, and cardiovascular protective effects, serving as a precursor in the biosynthesis of dihomo-gamma-linolenic acid and arachidonic acid .
2. Gamma linolenic Acid is employed in nutritional supplementation studies for conditions including rheumatoid arthritis, atopic dermatitis, diabetic neuropathy, and cyclical mastalgia, with research indicating it may help ease joint swelling and improve associated symptoms .
3. Gamma-linolenic acid is utilized as an analytical standard in gas chromatography and in nutritional studies regarding weight regain, mechanisms of fatty acid oxidation and peroxidation, and as a potential tumor suppression agent .
4. Researchers use Gamma linolenic Acid to study its effects on interleukin production in cell models, where it has been shown to decrease both IL-6 and IL-8 production in human enterocyte-like Caco-2 cells and dendritic cells in vitro .

1. Gamma-linolenic acid CAS 506-26-3 must be stored in a tightly sealed container at -20°C for long-term stability, protected from light, air, and heat; storage under inert gas is recommended to prevent oxidation .
2. Gamma linolenic Acid is classified with GHS signal word "Warning" and hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H413 (May cause long-lasting harmful effects to aquatic life); it is a moderate to severe irritant to the skin and eyes .
3. Personnel must wear chemical-resistant rubber gloves, safety goggles with side-shields, and impervious protective clothing when handling this substance, ensuring adequate ventilation in work areas and avoiding formation of dust and aerosols .
4. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition; avoid release to the environment and prevent entry into drains or water courses as the substance has WGK 3 water hazard classification .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable respirator when Gamma-linolenic acid CAS 506-26-3 is released .
2. Collect Gamma linolenic Acid spills by absorbing with finely-powdered liquid-binding materials such as diatomite or universal binders; for solid forms, sweep or vacuum without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Decontaminate surfaces and equipment by scrubbing with alcohol; avoid creating vapors or dust clouds during cleanup to prevent respiratory exposure .
4. Prevent Gamma linolenic Acid from entering drains, water courses, or the soil; dispose of collected material as hazardous waste according to local, state, and federal environmental regulations .

1. Gamma-linolenic acid CAS 506-26-3 is a combustible liquid with a flash point of 110°C (closed cup) and NFPA storage class of 10 (combustible liquids); under fire conditions, Gamma linolenic Acid may decompose and emit toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning Gamma-linolenic acid due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination and pollution .