Isopropyl 2-Bromo-2-methylpropionate CAS 51368-55-9

1. Isopropyl 2-Bromo-2-methylpropionate is a key intermediate in the synthesis of various pharmaceuticals, including the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen and other therapeutic agents .
2. Isopropyl 2-Bromo-2-methylpropionate CAS 51368-55-9 is used as a versatile building block in organic synthesis, particularly in nucleophilic substitution and alkylation reactions for constructing complex molecular structures .
3. Isopropyl 2-Bromo-2-methylpropionate serves as a precursor for the preparation of functionalized polymers and specialty chemicals in industrial applications .
4. Researchers utilize this product as a reagent for introducing the 2-methylpropionate moiety into target molecules in medicinal chemistry and drug discovery programs .

1. Isopropyl 2-Bromo-2-methylpropionate must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, away from heat, sparks, and open flames; recommended storage at 2-8°C .
2. Isopropyl 2-Bromo-2-methylpropionate CAS 51368-55-9 is classified with GHS hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep Isopropyl 2-Bromo-2-methylpropionate CAS 51368-55-9 away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition; wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable respirator when Isopropyl 2-Bromo-2-methylpropionate is released .
2. For liquid spills, contain and collect Isopropyl 2-Bromo-2-methylpropionate CAS 51368-55-9 using inert absorbent materials such as sand, diatomite, or universal binders with non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating vapors or mists during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. Isopropyl 2-Bromo-2-methylpropionate is a combustible liquid with a flash point of 51-52°C (closed cup) and may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and hydrogen bromide .
2. Use dry chemical powder, carbon dioxide, alcohol-resistant foam, or water spray to extinguish fires involving the product; do NOT use a direct water jet as Isopropyl 2-Bromo-2-methylpropionate CAS 51368-55-9 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning Isopropyl 2-Bromo-2-methylpropionate due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .