D-Mannose CAS 3458-28-4

1. D-Mannose CAS 3458-28-4 is a naturally occurring monosaccharide used as a dietary supplement for the prevention and treatment of urinary tract infections (UTIs), where D-Mannose inhibits bacterial adhesion to uroepithelial cells .
2. The compound serves as a key component in the synthesis of glycoproteins and glycolipids, and is utilized in cell culture media for studying glycosylation processes and protein folding .
3. D-Mannose is employed in biochemical research as a substrate for studying mannose metabolism, mannose-6-phosphate receptor interactions, and as a building block for oligosaccharide synthesis .
4. In the pharmaceutical and food industries, D-mannose is used as an excipient, sweetener, and as a starting material for the synthesis of D-mannitol and other sugar derivatives .

1. D-Mannose must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment at room temperature, protected from light and moisture .
2. D-Mannose is classified as non-hazardous under normal handling conditions according to GHS criteria, but may cause mild skin, eye, and respiratory tract irritation .
3. Personnel should wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, avoiding formation of dust and aerosols .
4. Keep D-Mannose away from incompatible materials such as strong oxidizing agents; the compound is hygroscopic and should be stored in a tightly sealed container to prevent moisture absorption .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when D-Mannose is released .
2. Collect D-Mannose by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent D-mannose from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations; the substance is considered non-hazardous for transport (DOT, IATA, IMDG) .

1. D-Mannose is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide and carbon dioxide .
2. Use D-Mannose water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning D-Mannose due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .