BOC-Glycine CAS 4530-20-5

1. BOC-Glycine is a protected amino acid derivative where the amino group of glycine is shielded by a tert-butyloxycarbonyl (BOC) group, serving as an essential building block for incorporating glycine residues into peptides during solid-phase peptide synthesis (SPPS) .
2. BOC-Glycine CAS 4530-20-5 is widely employed as an intermediate in organic synthesis for preparing pharmaceuticals, agrochemicals, and other fine chemicals, enabling selective deprotection under acidic conditions without affecting other protecting groups .
3. BOC-Glycine is utilized as a key reagent in the development of enzyme inhibitors, peptide-based therapeutics, and bioactive molecules, as well as a starting material for synthesizing hydantoins and other heterocyclic compounds .
4. Researchers use BOC-Glycine CAS 4530-20-5 to study protein structure-function relationships, introduce conformational flexibility into peptides, and develop peptide-based drugs with enhanced metabolic stability .

1. BOC-Glycine must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment; recommended storage at 2-8°C for short-term or -20°C for long-term stability (up to 3 years) .
2. BOC-Glycine CAS 4530-20-5 is classified with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" according to some suppliers .
3. Personnel should wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, avoiding formation of dust and aerosols .
4. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition ; the compound is soluble in organic solvents including DMF, DMSO, and ethanol but poorly soluble in water .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when BOC-Glycine is released .
2. Collect BOC-Glycine CAS 4530-20-5 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses as discharge into the environment should be avoided .
4. Dispose of collected BOC-Glycine CAS 4530-20-5 material as non-hazardous waste according to local, state, and federal environmental regulations, offering surplus and non-recyclable solutions to a licensed disposal company .

1. BOC-Glycine is not classified as highly flammable with NFPA fire rating of 1 (materials that require considerable preheating before ignition); under fire conditions, hazardous decomposition products include toxic fumes of carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use BOC-Glycine CAS 4530-20-5 water spray, alcohol-resistant foam, dry chemical powder, or carbon dioxide to extinguish fires involving the product; do NOT use a direct water jet as it may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning BOC-Glycine due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; move containers from the fire area if safe to do so, and contain fire runoff to prevent environmental contamination .