Ursolic Acid CAS 77-52-1

1. Ursolic acid is a naturally occurring pentacyclic triterpenoid found in many medicinal herbs and edible fruits, primarily used in research for its anti-inflammatory, antioxidant, anticancer, and hepatoprotective properties .
2. Ursolic Acid CAS 77-52-1 has been shown to inhibit cancer cell proliferation, induce apoptosis, and suppress tumor metastasis through modulation of multiple signaling pathways including STAT3, NF-κB, and PI3K/Akt .
3. Ursolic acid is utilized in metabolic research for its antidiabetic and anti-obesity effects, where it improves insulin sensitivity, enhances glucose uptake, and promotes brown fat thermogenesis .
4. In formulation research, ursolic acid is used to develop nanoformulations and delivery systems to overcome its poor water solubility and enhance bioavailability for therapeutic applications .

1. Ursolic acid must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment; powder is stable for up to 3 years at -20°C or 2 years at 4°C, protected from light and moisture .
2. For solution storage, prepare aliquots in tightly sealed vials and store at -20°C for up to 1 month or at -80°C for up to 6 months, avoiding repeated freeze-thaw cycles to prevent degradation .
3. Ursolic Acid CAS 77-52-1 is classified with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" .
4. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas and avoiding formation of dust and aerosols .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when Ursolic acid is released .
2. Collect Ursolic Acid CAS 77-52-1 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. Ursolic acid is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as Ursolic Acid CAS 77-52-1 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning Ursolic acid due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; move containers from the fire area if safe to do so, and contain fire runoff to prevent environmental contamination .