Indacaterol Maleate CAS 753498-25-8

1. Indacaterol Maleate is primarily used as an ultra-long-acting β₂-adrenoceptor agonist for the once-daily maintenance treatment of chronic obstructive pulmonary disease (COPD) to improve lung function and patient-reported outcomes .
2. Indacaterol Maleate CAS 753498-25-8 functions by stimulating intracellular adenyl cyclase, increasing cyclic AMP levels which cause relaxation of bronchial smooth muscle, with an onset of action within 5 minutes and a duration of bronchodilation of at least 24 hours .
3. Indacaterol Maleate is employed in clinical research to investigate its effects during acute exacerbations of COPD (AECOPD), where studies have demonstrated greater improvement in pulmonary function compared to traditional therapy without cardiovascular side effects .
4. Researchers utilize Indacaterol Maleate CAS 753498-25-8 in real-world post-marketing surveillance studies to evaluate long-term safety and efficacy, with data showing favorable tolerability profiles and improvements in COPD assessment test (CAT) scores and lung function parameters .

1. Indacaterol Maleate must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment; in lyophilized powder form, it is stable for up to 3 years at -20°C or 2 years at 4°C, while solutions should be stored at -80°C for up to 6 months or -20°C for 1 month .
2. Indacaterol Maleate CAS 753498-25-8 should be protected from light, heat, and direct sunlight, and kept away from incompatible materials such as strong acids/alkalis and strong oxidizing/reducing agents to prevent decomposition .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, impervious protective clothing, and suitable respirators when handling Indacaterol Maleate, ensuring adequate ventilation and avoiding dust and aerosol formation .
4. Avoid inhalation, contact with eyes and skin; if exposed, immediately relocate to fresh air, rinse skin or eyes thoroughly with water, and seek medical attention. Do NOT induce vomiting if ingested .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable respirator when Indacaterol Maleate is released .
2. Absorb solutions with finely-powdered liquid-binding materials such as diatomite or universal binders; collect spilled solid by sweeping or vacuuming without creating dust, using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating Indacaterol Maleate CAS 753498-25-8 dust or vapor clouds during cleanup to prevent respiratory exposure, decontaminate surfaces and equipment by scrubbing with alcohol, and prevent the product from entering drains or water courses due to potential environmental hazards .
4. Dispose of collected material according to local, state, and federal environmental regulations, as runoff from fire control or dilution water may cause pollution .

1. Indacaterol Maleate is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes and irritant fumes during combustion .
2. Use water spray, dry chemical powder, foam, or carbon dioxide fire extinguishers to extinguish fires involving the product, selecting appropriate extinguishing media based on surrounding environment .
3. Firefighters Indacaterol Maleate CAS 753498-25-8 should wear self-contained breathing apparatus and full protective gear when handling burning Indacaterol Maleate due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant fumes; move containers from the fire area if safe to do so, cool exposed containers with water spray, and contain fire runoff to prevent environmental contamination and pollution .