1-Bromo-2-iodobenzene CAS 583-55-1

1. 1-Bromo-2-iodobenzene CAS 583-55-1 is primarily used as a versatile electrophile and building block in organic synthesis, enabling the formation of carbon-carbon bonds via palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Heck reactions .
2. 1-Bromo-2-iodobenzene serves as a key intermediate in pharmaceutical research for synthesizing biologically active molecules, including diarylamines and potential therapeutic agents for various diseases .
3. Applications of 1-Bromo-2-iodobenzene also include its use in materials science for developing functional materials like liquid crystals and polymers, as well as a reagent in analytical chemistry .

1. Store 1-Bromo-2-iodobenzene CAS 583-55-1 in a tightly sealed container, protected from light, in a cool, dry, and well-ventilated area; recommended storage temperatures range from 0-8°C (refrigerated) to -20°C for long-term stability .
2. Keep 1-Bromo-2-iodobenzene away from strong oxidizing agents and bases, as it is light-sensitive and may decompose upon exposure to light .
3. Always use 1-Bromo-2-iodobenzene appropriate personal protective equipment (PPE) including chemical-resistant gloves and safety goggles when handling 1-Bromo-2-iodobenzene, and ensure adequate ventilation to avoid breathing vapors .

1. Immediately isolate the spill area, eliminate all ignition sources, and contain 1-Bromo-2-iodobenzene CAS 583-55-1 using inert, non-combustible absorbent material; prevent entry into drains or waterways .
2. Carefully collect 1-Bromo-2-iodobenzene into a sealed, labeled chemical waste container for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must wear suitable PPE during cleanup; 1-Bromo-2-iodobenzene is typically not classified as hazardous material for transport by some regulations .

1. 1-Bromo-2-iodobenzene CAS 583-55-1 is classified with GHS signal word "Warning" and causes skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335) .
2. 1-Bromo-2-iodobenzene is combustible with a flash point of 110-113°C; thermal decomposition or combustion can produce toxic and corrosive fumes including hydrogen bromide, hydrogen iodide, and carbon oxides .
3. Always consult 1-Bromo-2-iodobenzene the specific Safety Data Sheet (SDS) for 1-Bromo-2-iodobenzene for complete hazard information, first-aid procedures, and handling instructions; precautionary statements include P261 (avoid breathing vapors), P280 (wear protective gloves/eye protection), and P304+P340 (if inhaled) .