2-Nitrobenzaldehyde CAS 552-89-6

1. 2-Nitrobenzaldehyde CAS 552-89-6 is primarily used as a key organic synthesis intermediate, particularly in the pharmaceutical industry for manufacturing anti-anginal drugs like nifedipine . It also serves as a reagent for testing acetone .
2. 2-Nitrobenzaldehyde is a crucial intermediate in the historic Baeyer-Drewsen synthesis of indigo dye and is widely utilized in research for synthesizing pharmaceuticals, such as anti-inflammatory agents, and for developing specialty polymers with enhanced thermal stability .
3. Applications of 2-Nitrobenzaldehyde also include its use in analytical chemistry (e.g., spectrophotometry), in the design of fluorescent probes for biological imaging , and as a photoremovable protecting group for various chemical functions .

1. Store 2-Nitrobenzaldehyde CAS 552-89-6 in a tightly sealed container in a cool, dry, and well-ventilated area, protected from light and moisture, and away from incompatible materials . Recommended storage temperatures range from room temperature (RT) to 4°C or -20°C for long-term stability.
2. Keep 2-Nitrobenzaldehyde strictly away from strong oxidizing agents, strong reducing agents, and strong bases to prevent hazardous decomposition .
3. Always 2-Nitrobenzaldehyde use appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing; minimize dust generation and avoid breathing dust, and handle only with adequate ventilation .

1. Immediately isolate the spill area and eliminate all ignition sources. Contain 2-Nitrobenzaldehyde CAS 552-89-6 using inert, non-combustible absorbent material, and avoid generating dusty conditions .
2. Carefully sweep up 2-Nitrobenzaldehyde using clean, non-sparking tools and place the collected material into a sealed, labeled chemical waste container for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must wear suitable PPE, including protective gloves and eye/face protection, during cleanup ; prevent material from entering drains or waterways .

1. 2-Nitrobenzaldehyde CAS 552-89-6 is classified as harmful if swallowed (H302), causes skin irritation (H315) and serious eye irritation (H319), and may cause respiratory irritation (H335) . 2-Nitrobenzaldehyde is also noted as a potential mutagen .
2. 2-Nitrobenzaldehyde is combustible with a flash point >110°C ; during a fire, irritating and highly toxic gases (e.g., nitrogen oxides, carbon monoxide) may be generated by thermal decomposition or combustion . 2-Nitrobenzaldehyde CAS 552-89-6 is also harmful to aquatic life with long-lasting effects .
3. Always consult the specific Safety Data Sheet (SDS) for 2-Nitrobenzaldehyde for complete hazard information, first-aid procedures, and handling instructions .