2'-Hydroxyacetophenone CAS 118-93-4

1. 2'-Hydroxyacetophenone is a versatile building block in organic synthesis, particularly for preparing pharmaceuticals (e.g., potential anti-cancer agents), agrochemicals, and dyes . It serves as a raw material to synthesize Schiff bases, benzopyrans, and other biologically active compounds .
2. 2'-Hydroxyacetophenone CAS 118-93-4 is approved as a flavoring ingredient in food, contributing phenolic, sweet, and cherry pit-like notes, and is naturally present in tomatoes, coffee, cocoa, and alcoholic beverages .
3. Applications of 2'-Hydroxyacetophenone also include its use in polymer synthesis as a functional monomer and as an analytical reference standard in chromatography and spectroscopy .

1. Store 2'-Hydroxyacetophenone in a tightly sealed container in a cool, dry, and well-ventilated area, protected from direct sunlight and ignition sources . Recommended storage for long-term stability is at -20°C or under refrigeration (2-8°C) .
2. Keep 2'-Hydroxyacetophenone away from strong oxidizing agents, strong acids/alkalis, and reducing agents to prevent hazardous decomposition reactions .
3. Always 2'-Hydroxyacetophenone CAS 118-93-4 use appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing; handle only with adequate ventilation (fume hood) and avoid breathing dust, vapors, or mist .

1. Immediately isolate the spill area, eliminate all ignition sources, and contain 2'-Hydroxyacetophenone using inert, non-combustible absorbent material (e.g., dry sand, diatomite) . Prevent material from entering drains or waterways .
2. Carefully sweep up 2'-Hydroxyacetophenone CAS 118-93-4 using clean, non-sparking tools, or absorb solutions with liquid-binding material; decontaminate surfaces and equipment by scrubbing with alcohol .
3. Place all collected material and contaminated items into sealed, labeled chemical waste containers for proper disposal according to local, state, and federal environmental regulations .

1. 2'-Hydroxyacetophenone is classified as a skin irritant (H315) and a serious eye irritant (H319), and may cause respiratory tract irritation (H335) . It has an acute intraperitoneal LD50 of 100 mg/kg in mice and is considered a dermatotoxin .
2. 2'-Hydroxyacetophenone is combustible with a flash point of 88-112°C; its thermal decomposition can produce toxic and irritating fumes including carbon monoxide and carbon dioxide . It is generally non-hazardous for transport (DOT, IATA) .
3. Always 2'-Hydroxyacetophenone CAS 118-93-4 consult the specific Safety Data Sheet (SDS) for 2'-Hydroxyacetophenone for complete hazard information, first-aid procedures (P305+P351+P338 for eyes, P301+P330+P331 for ingestion), and handling instructions.